C H Yam
Overview
Explore the profile of C H Yam including associated specialties, affiliations and a list of published articles.
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10
Citations
399
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Recent Articles
1.
Yam C, Fung T, Poon R
Cell Mol Life Sci
. 2002 Oct;
59(8):1317-26.
PMID: 12363035
Cyclin A is particularly interesting among the cyclin family because it can activate two different cyclin-dependent kinases (CDKs) and functions in both S phase and mitosis. An embryonic form of...
2.
A re-visit on seasonal variations in suicides in the Hong Kong Special Administrative Region (HKSAR)
Yip P, Yam C, Chau P
Acta Psychiatr Scand
. 2001 May;
103(4):315-6.
PMID: 11328249
No abstract available.
3.
Yam C, Siu W, Kaganovich D, Ruderman J, Poon R
Proc Natl Acad Sci U S A
. 2001 Jan;
98(2):497-501.
PMID: 11136238
Previous work has shown that cyclin A can be cleaved at Arg-70/Arg-71 by a proteolytic activity present in an in vitro-coupled transcription/translation system by using rabbit reticulocyte lysate programmed by...
4.
Arooz T, Yam C, Siu W, Lau A, Li K, Poon R
Biochemistry
. 2000 Aug;
39(31):9494-501.
PMID: 10924145
Cyclins and cyclin-dependent kinases (CDKs) are key regulators of the human cell cycle. Here we have directly measured the concentrations of the G(1) and G(2) cyclins and their CDK partners...
5.
Yam C, Siu W, Lau A, Poon R
J Biol Chem
. 2000 Feb;
275(5):3158-67.
PMID: 10652300
Many cyclins are degraded by the ubiquitination/proteasome pathways involving the anaphase-promoting complex and SCF complexes. These degradations are frequently dependent on phosphorylation by cyclin-dependent kinases (CDKs), providing a self-limiting mechanism...
6.
Yeung P, New D, Leveson A, Yam C, Poon R, Wong J
Exp Cell Res
. 2000 Jan;
254(1):120-9.
PMID: 10623472
Dinoflagellates are a major group of organisms with an extranuclear spindle. As the purpose of the spindle checkpoint is to ensure proper alignment of the chromosomes on the spindle, dinoflagellate...
7.
Siu W, Yam C, Poon R
FEBS Lett
. 1999 Nov;
461(3):299-305.
PMID: 10567715
Cell cycle arrest after different types of DNA damage can occur in either G1 phase or G2 phase of the cell cycle, involving the distinct mechanisms of p53/p21(Cip1/Waf1) induction, and...
8.
Yam C, Siu W, Arooz T, Chiu C, Lau A, Wang X, et al.
Cancer Res
. 1999 Oct;
59(20):5075-8.
PMID: 10537276
Transforming growth factor-beta (TGF-beta) inhibits cell proliferation in many cell types, and acquisition of TGF-beta resistance has been linked to tumorigenesis. One class of proteins that plays a key role...
9.
Yam C, Ng R, Siu W, Lau A, Poon R
Mol Cell Biol
. 1998 Dec;
19(1):635-45.
PMID: 9858587
Cyclin A-Cdk2 complexes bind to Skp1 and Skp2 during S phase, but the function of Skp1 and Skp2 is unclear. Skp1, together with F-box proteins like Skp2, are part of...
10.
Ng R, Arooz T, Yam C, Chan I, Lau A, Poon R
FEBS Lett
. 1998 Nov;
438(3):183-9.
PMID: 9827542
Skp1 interacts with cullins, F-box containing proteins, and forms a complex with cyclin A-Cdk2 in mammalian cells. Skp1 is also involved in diverse biological processes like degradation of key cell...