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C H Buys

Explore the profile of C H Buys including associated specialties, affiliations and a list of published articles. Areas
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Articles 176
Citations 2110
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Recent Articles
1.
Berends M, Wu Y, Sijmons R, Hofstra R, van der Zee A, Buys C, et al.
Scand J Gastroenterol Suppl . 2002 Jan; (234):61-7. PMID: 11768563
Hereditary non-polyposis colorectal cancer is an autosomal dominant inherited disorder that predisposes its carriers to an almost 100% lifetime risk of cancer, in particular colorectal and endometrial cancer. Germline mutations,...
2.
Carvalho B, Van der Veen A, Gartner F, Carneiro F, Seruca R, Buys C, et al.
Cancer Genet Cytogenet . 2001 Dec; 131(1):54-9. PMID: 11734319
In gastric cancer, alterations in the long arm of chromosome 6 are a frequent event. Two regions of heterozygous loss have been described: 6q16.3-6q23 and 6q26-6q27. We have evaluated by...
3.
Boon M, Nolte I, Bruinenberg M, Spijker G, Terpstra P, Raelson J, et al.
Neurogenetics . 2001 Nov; 3(4):221-30. PMID: 11714103
Multiple sclerosis (MS) is a complex disease that is partly genetic in origin. Although an association of MS with specific human leukocyte antigen (HLA) types has been known for almost...
4.
Wu Y, Berends M, Sijmons R, Mensink R, Verlind E, Kooi K, et al.
Nat Genet . 2001 Oct; 29(2):137-8. PMID: 11586295
We investigated a possible role of the mismatch-repair gene MLH3 in hereditary nonpolyposis colorectal cancer by scanning for mutations in 39 HNPCC families and in 288 patients suspected of having...
5.
Schuringa J, Wojtachnio K, HAGENS W, Vellenga E, Buys C, HOFSTRA R, et al.
Oncogene . 2001 Sep; 20(38):5350-8. PMID: 11536047
The MEN2A oncogene encodes for a constitutive active member of the RET receptor tyrosine kinase family. Here, we report that MEN2A-RET activates Signal Transducer and Activator of Transcription 3 (STAT3)...
6.
Wu Y, Berends M, Post J, Mensink R, Verlind E, van der Sluis T, et al.
Gastroenterology . 2001 May; 120(7):1580-7. PMID: 11375940
Background & Aims: Germline mutations in one of four mismatch repair genes have been found in the majority of families with hereditary nonpolyposis colorectal cancer (HNPCC), but only in a...
7.
McLaughlin P, Harmsen M, Dokter W, Kroesen B, van der Molen H, Brinker M, et al.
Cancer Res . 2001 May; 61(10):4105-11. PMID: 11358833
The human pancarcinoma-associated epithelial glycoprotein-2 (EGP-2), a M(r) 38,000 transmembrane antigen also known as 17-1A or Ep-CAM, is commonly used for targeted immunotherapy of carcinomas because it is strongly expressed...
8.
Berends M, Hollema H, Wu Y, van der Sluis T, Mensink R, ten Hoor K, et al.
Int J Cancer . 2001 Apr; 92(3):398-403. PMID: 11291077
The predictive value of MLH1 or MSH2 protein expression for the presence of truncating germline mutations was examined in benign and (pre)malignant endometrial samples from 3 patient groups: (I) 10...
9.
Bleeker W, Hayes V, Karrenbeld A, Hofstra R, Verlind E, Hermans J, et al.
Dis Colon Rectum . 2001 Apr; 44(3):358-63. PMID: 11289281
Purpose: Mutations in K-ras and TP53 genes are common in colorectal cancer. They affect biologic behavior and might influence chemotherapy susceptibility in these tumors. We investigated whether the survival of...
10.
van der Steege G, Buys C, Scheffer H, Pas H, Jonkman M
Nat Biotechnol . 2001 Apr; 19(4):305-6. PMID: 11283576
No abstract available.