C Guillemette
Overview
Explore the profile of C Guillemette including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
697
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Recent Articles
1.
Levesque E, Delage R, Benoit-Biancamano M, Caron P, Bernard O, Couture F, et al.
Clin J Am Soc Nephrol
. 2023 Mar;
3(1):7-9.
PMID: 37001056
No abstract available.
2.
Tourancheau A, Rouleau M, Guauque-Olarte S, Villeneuve L, Gilbert I, Droit A, et al.
Pharmacogenomics J
. 2017 Apr;
18(2):251-261.
PMID: 28440341
Alternative splicing as a mean to control gene expression and diversify function is suspected to considerably influence drug response and clearance. We report the quantitative expression profiles of the human...
3.
Cook M, Wood S, Hyland P, Caron P, Drahos J, Falk R, et al.
Andrology
. 2017 Feb;
5(2):240-247.
PMID: 28241109
Previously, we observed strong positive associations between circulating concentrations of free testosterone and free dihydrotestosterone (DHT) in relation to Barrett's esophagus in a US male military population. To replicate these...
4.
Bergeron A, Hebert A, Guillemette C, Laroche A, Poulin M, Aragon J, et al.
Andrology
. 2016 Nov;
5(1):169-179.
PMID: 27860455
Cyclic adenosine monophosphate (cAMP) plays a crucial role as a signaling molecule for capacitation, motility, and acrosome reaction in mammalian spermatozoa. It is well-known that cAMP degradation by phosphodiesterase (PDE)...
5.
Bergeron A, Aragon J, Guillemette C, Hebert A, Sullivan R, Blondin P, et al.
Andrology
. 2016 Aug;
4(6):1123-1130.
PMID: 27565610
The second messenger cyclic adenosine monophosphate (cAMP) has a central role in sperm physiology. Extracellular cAMP can be sequentially degraded into 5'AMP and adenosine by ecto-phosphodiesterases (ecto-PDE) and ecto-nucleotidases, a...
6.
Gammal R, Court M, Haidar C, Iwuchukwu O, Gaur A, Alvarellos M, et al.
Clin Pharmacol Ther
. 2015 Sep;
99(4):363-9.
PMID: 26417955
The antiretroviral protease inhibitor atazanavir inhibits hepatic uridine diphosphate glucuronosyltransferase (UGT) 1A1, thereby preventing the glucuronidation and elimination of bilirubin. Resultant indirect hyperbilirubinemia with jaundice can cause premature discontinuation of...
7.
Khan D, Guillemette C, Sirard M, Richard F
Mol Hum Reprod
. 2015 Jun;
21(9):688-701.
PMID: 26113519
Understanding the mechanisms regulating oocyte developmental competence is essential to enhance the clinical efficiency of assisted reproduction. FSH orchestrates the acquisition of oocyte competence, both in vivo and in vitro....
8.
Khan D, Guillemette C, Sirard M, Richard F
Physiol Genomics
. 2015 Jun;
47(9):432-42.
PMID: 26082143
Acquisition of oocyte developmental competence needs to be understood to improve clinical outcomes of assisted reproduction. The stimulation of cumulus cell concentration of cyclic adenosine 3'5'-monophosphate (cAMP) by pharmacological agents...
9.
Tourancheau A, Margaillan G, Rouleau M, Gilbert I, Villeneuve L, Levesque E, et al.
Pharmacogenomics J
. 2015 Apr;
16(1):60-70.
PMID: 25869014
A comprehensive view of the human UDP-glucuronosyltransferase (UGT) transcriptome is a prerequisite to the establishment of an individual's UGT metabolic glucuronidation signature. Here, we uncover the transcriptome landscape of the...
10.
Chen S, Laverdiere I, Tourancheau A, Jonker D, Couture F, Cecchin E, et al.
Pharmacogenomics J
. 2015 Mar;
15(6):513-20.
PMID: 25778466
The risk of severe irinotecan-induced neutropenia has been shown to be related to the UGT1 variant UGT1A1*28, which increases exposure to the potent metabolite SN-38. Our goal was to identify...