C G Mathew
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Explore the profile of C G Mathew including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Osler T, Schoeman M, Edge J, Pretorius W, Rabe F, Mathew C, et al.
Cancer Med
. 2025 Mar;
14(5):e70743.
PMID: 40042150
Purpose: Limited data exist on managing hereditary breast cancer in low- middle-income countries (LMICs). We assessed proband and cascade genetic testing, and risk-reducing measures in a South African regional breast...
2.
Osler T, Schoeman M, Pretorius W, Mathew C, Edge J, Urban M
Breast Cancer Res Treat
. 2025 Jan;
PMID: 39776011
Purpose: Breast cancer (BC) is the commonest cancer in South African women. A proportion are associated with a pathogenic or likely pathogenic (P/LP) variant in a BC susceptibility gene. Clinical...
3.
Schwerd T, Bryant R, Pandey S, Capitani M, Meran L, Cazier J, et al.
Mucosal Immunol
. 2017 Nov;
11(2):562-574.
PMID: 29091079
Genetic defects that affect intestinal epithelial barrier function can present with very early-onset inflammatory bowel disease (VEOIBD). Using whole-genome sequencing, a novel hemizygous defect in NOX1 encoding NAPDH oxidase 1...
4.
Murphy G, McCormack V, Abedi-Ardekani B, Arnold M, Camargo M, Dar N, et al.
Ann Oncol
. 2017 Sep;
28(9):2086-2093.
PMID: 28911061
The International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI) have initiated a series of cancer-focused seminars [Scelo G, Hofmann JN, Banks RE et al....
5.
Elliott T, Hudspith B, Rayment N, Prescott N, Petrovska L, Hermon-Taylor J, et al.
J Gastroenterol Hepatol
. 2015 Mar;
30(8):1265-74.
PMID: 25809337
Background And Aim: Escherichia coli can be isolated from lamina propria macrophages in Crohn's disease (CD), and their intramacrophage persistence may provide a stimulus for inflammation. To further determine the...
6.
Mathew C
Methods Mol Biol
. 2011 Mar;
2:257-61.
PMID: 21374202
Nick translation is the name given to a reaction that is used to replace cold nucleoside triphosphates in a double-stranded DNA molecule with radioactive ones (1,2). Free 3'-hydroxyl groups are...
7.
Mathew C
Methods Mol Biol
. 2011 Mar;
2:55-66.
PMID: 21374173
The purpose of this technique is the detection and characterization of specific DNA sequences. The DNA is fragmented by digestion with a restriction endonuclease, and the fragments separated by agarose...
8.
Mathew C
Methods Mol Biol
. 2011 Mar;
2:31-4.
PMID: 21374169
The isolation of high molecular weight eukaryotic DNA in good yield is an important prerequisite for the analysis of specific sequences by Southern blotting ( Chapter 9 ), or for...
9.
Wilson J, Yamamoto K, Marriott A, Hussain S, Sung P, Hoatlin M, et al.
Oncogene
. 2008 Jan;
27(26):3641-52.
PMID: 18212739
Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. Thirteen complementation groups and genes are identified, including BRCA2, which...
10.
Wolf N, Quaranta M, Prescott N, Allen M, Smith R, Burden A, et al.
J Med Genet
. 2007 Nov;
45(2):114-6.
PMID: 17993580
Background: Psoriasis is an immune-mediated skin disorder that is inherited as a multifactorial trait. Linkage analyses have clearly mapped a primary disease susceptibility locus to the major histocompatibility complex (MHC)...