C G Kevil
Overview
Explore the profile of C G Kevil including associated specialties, affiliations and a list of published articles.
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22
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605
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Recent Articles
1.
Kurmaeva E, Lord J, Zhang S, Bao J, Kevil C, Grisham M, et al.
Mucosal Immunol
. 2014 Apr;
7(6):1354-65.
PMID: 24717354
Anti-adhesion therapies that target α(4) integrins (e.g., natalizumab) are thought to work by blocking T-cell recruitment to the intestinal tissues in patients with Crohn's disease (CD); however, little direct evidence...
2.
Titova E, Kevil C, Ostrowski R, Rojas H, Liu S, Zhang J, et al.
Acta Neurochir Suppl
. 2008 Dec;
105:85-7.
PMID: 19066088
Experimental studies of intracerebral hemorrhage (ICH) point toward leukocytes as a major contributor to ICH-induced brain injury. Leukocyte and endothelial cell adhesion molecules are responsible for injurious neutrophil-endothelial cell interactions...
3.
Kevil C, Pruitt H, Kavanagh T, Wilkerson J, Farin F, Moellering D, et al.
FASEB J
. 2004 Jun;
18(11):1321-3.
PMID: 15180961
The role of glutathione (GSH) in inflammation is largely discussed from the context of providing reducing equivalents to detoxify reactive oxygen and nitrogen species. Inflammation is now recognized to be...
4.
Kevil C, Okayama N, Alexander J
Am J Physiol Cell Physiol
. 2001 Nov;
281(6):C1940-7.
PMID: 11698252
We previously reported that exposure of endothelial cells to H(2)O(2) results in a loss of cell-cell apposition and increased endothelial solute permeability. The purpose of this study was to determine...
5.
Kevil C, Bullard D
Acta Physiol Scand
. 2001 Oct;
173(1):151-7.
PMID: 11678738
Endothelial cells play a crucial role in maintaining cardiovascular homeostasis. Although many cardiovascular disorders involve endothelial cell dysfunction, the specific cellular and molecular mechanisms involved are not well known. We...
6.
Kevil C, Patel R, Bullard D
Am J Physiol Cell Physiol
. 2001 Oct;
281(5):C1442-7.
PMID: 11600406
Monocyte-endothelial cell interactions have been implicated in the pathogenesis of a number of vascular diseases that target arterial and aortic endothelium, including atherosclerosis. Many different adhesion molecules, such as intercellular...
7.
Kevil C, Oshima T, Alexander J
Endothelium
. 2001 Sep;
8(2):107-16.
PMID: 11572474
Objective: The purpose of this study was to determine the contribution of p38 MAP kinase activity during hydrogen peroxide mediated increased endothelial solute permeability. We also sought to identify the...
8.
Jones S, Trocha S, Strange M, Granger D, Kevil C, Bullard D, et al.
Am J Physiol Heart Circ Physiol
. 2000 Oct;
279(5):H2196-201.
PMID: 11045953
Expression of endothelial and leukocyte cell adhesion molecules is a principal determinant of polymorphonuclear neutrophil (PMN) recruitment during inflammation. It has been demonstrated that pharmacological inhibition of these molecules can...
9.
Kevil C, Oshima T, Alexander B, Coe L, Alexander J
Am J Physiol Cell Physiol
. 2000 Jul;
279(1):C21-30.
PMID: 10898713
H(2)O(2)-mediated elevation in endothelial solute permeability is associated with pathological events such as ischemia-reperfusion and inflammation. To understand how H(2)O(2) mediates increased permeability, we investigated the effects of H(2)O(2) administration...
10.
Alexander J, Alexander B, Eppihimer L, Goodyear N, Haque R, Davis C, et al.
Inflammation
. 2000 Mar;
24(2):99-113.
PMID: 10718113
The mechanisms through which inflammatory mediators modify endothelial junctional structure are not well understood. Endothelial cells exposed to 1 mM H2O2, 0.1 mM histamine or 4 mM EDTA displayed decreased...