C E Holt
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Explore the profile of C E Holt including associated specialties, affiliations and a list of published articles.
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68
Citations
2205
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Recent Articles
1.
Shinnick T, Pallotta D, Jones-Brown Y, Youngman P, Holt C
Curr Microbiol
. 2013 Jan;
1(3):163-6.
PMID: 23338142
Mating inPhysarum polycephalum involves the fusion of two haploid amoebae and the differentiation of the resulting diploid zygote into a multinucleate plasmodium. Mating proceeds optimally with amoebae growing on an...
2.
3.
McFarlane S, Holt C
Trends Cell Biol
. 2007 Aug;
7(11):424-30.
PMID: 17708999
A remarkable finding to emerge in recent years is that the early brain neuroepithelium is highly patterned before axonogenesis begins. Growth factors are among a variety of classes of molecules...
4.
Shewan D, Dwivedy A, Anderson R, Holt C
Nat Neurosci
. 2002 Sep;
5(10):955-62.
PMID: 12352982
Retinal axons are led out of the eye by netrin-1, an attractive guidance cue which is secreted at the optic nerve head. In the optic pathway, however, netrin-1 is expressed...
5.
Campbell D, Holt C
Neuron
. 2002 Jan;
32(6):1013-26.
PMID: 11754834
Growth cones contain mRNAs, translation machinery, and, as we report here, protein degradation machinery. We show that isolated retinal growth cones immediately lose their ability to turn in a chemotropic...
6.
Campbell D, Regan A, Lopez J, Tannahill D, Harris W, Holt C
J Neurosci
. 2001 Oct;
21(21):8538-47.
PMID: 11606642
The semaphorin receptor, neuropilin-1 (NP-1), was first identified in Xenopus as the A5 antigen and is expressed abundantly in developing retinal ganglion cells (RGCs). Here we show that growth cones...
7.
Johnson K, McKinnell I, Stoker A, Holt C
J Neurobiol
. 2001 Oct;
49(2):99-117.
PMID: 11598918
Receptor protein tyrosine phosphatases (RPTPs) are regulators of axon outgrowth and guidance in a variety of different vertebrate and invertebrate systems. Three RPTPs, CRYP-alpha, PTP-delta, and LAR, are expressed in...
8.
Nutt S, Dingwell K, Holt C, Amaya E
Genes Dev
. 2001 May;
15(9):1152-66.
PMID: 11331610
Signal transduction through the FGF receptor is essential for the specification of the vertebrate body plan. Blocking the FGF pathway in early Xenopus embryos inhibits mesoderm induction and results in...
9.
Mann F, Holt C
Bioessays
. 2001 Mar;
23(4):319-26.
PMID: 11268037
Metamorphosis in frogs is a critical developmental process through which a tadpole changes into an adult froglet. Metamorphic changes include external morphological transformations as well as important changes in the...
10.
Dingwell K, Holt C, Harris W
J Neurobiol
. 2000 Aug;
44(2):246-59.
PMID: 10934326
Retinal ganglion cells (RGCs) of Xenopus laevis send axons along a stereospecific pathway from the retina to their target the optic tectum. Viewed from the point of the growth cone,...