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C E Brightling

Explore the profile of C E Brightling including associated specialties, affiliations and a list of published articles. Areas
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Articles 81
Citations 2827
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Recent Articles
1.
Bousquet J, Melen E, Haahtela T, Koppelman G, Togias A, Valenta R, et al.
Allergy . 2023 Feb; 78(5):1169-1203. PMID: 36799120
Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach...
2.
Bhavra K, Wilde M, Richardson M, Cordell R, Thomas P, Zhao B, et al.
J Breath Res . 2022 Feb; 16(2). PMID: 35168217
Clinical assessment of children with asthma is problematic, and non-invasive biomarkers are needed urgently. Monitoring exhaled volatile organic compounds (VOCs) is an attractive alternative to invasive tests (blood and sputum)...
3.
John E, Abrams K, Brightling C, Sheehan N
BMC Med Res Methodol . 2019 Nov; 19(1):207. PMID: 31726969
Background: Recently, there has been a heightened interest in developing and evaluating different methods for analysing observational data. This has been driven by the increased availability of large data resources...
4.
Diver S, Russell R, Brightling C
Clin Exp Allergy . 2018 Jan; 48(3):241-252. PMID: 29315966
Asthma is a common chronic inflammatory condition of the airways affecting over 300 million people world-wide. In 5%-10% of cases, it is severe, with disproportionate healthcare resource utilization including costs...
5.
Bilocca D, Hargadon B, Pavord I, Green R, Brightling C, Bradding P, et al.
Chron Respir Dis . 2017 Jun; 15(1):85-87. PMID: 28569072
The use of oral methotrexate for refractory eosinophilic asthma in a tertiary asthma referral centre, Glenfield Hospital, Leicester, was evaluated between January 2006 and December 2014. The patients ( n...
6.
Sousa A, Marshall R, Warnock L, Bolton S, Hastie A, Symon F, et al.
Clin Exp Allergy . 2017 May; 47(7):890-899. PMID: 28493293
Background: Patients with severe asthma appear relatively corticosteroid resistant. Corticosteroid responsiveness is closely related to the degree of eosinophilic airway inflammation. The extent to which eosinophilic airway inflammation in severe...
7.
Bousquet J, Farrell J, Crooks G, Hellings P, Bel E, Bewick M, et al.
Clin Transl Allergy . 2017 Feb; 7:5. PMID: 28239450
[This corrects the article DOI: 10.1186/s13601-016-0116-9.].
8.
Bousquet J, Hellings P, Agache I, Bedbrook A, Bachert C, Bergmann K, et al.
Clin Transl Allergy . 2017 Jan; 6:47. PMID: 28050247
The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis...
9.
Bousquet J, Bewick M, Cano A, Eklund P, Fico G, Goswami N, et al.
J Nutr Health Aging . 2016 Dec; 21(1):92-104. PMID: 27999855
The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have...
10.
Wright A, Newby C, Hartley R, Mistry V, Gupta S, Berair R, et al.
Allergy . 2016 Oct; 72(4):645-655. PMID: 27709630
Background: The role of fibrocytes in chronic obstructive pulmonary disease (COPD) is unknown. We sought to enumerate blood and tissue fibrocytes in COPD and determine the association of blood fibrocytes...