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C David Wood

Explore the profile of C David Wood including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 718
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Recent Articles
1.
Campos-Leon K, Ferguson J, Gunther T, Wood C, Wingett S, Pekel S, et al.
PLoS Pathog . 2025 Jan; 21(1):e1012506. PMID: 39869645
Upon infection, human papillomavirus (HPV) manipulates host cell gene expression to create an environment that is supportive of a productive and persistent infection. The virus-induced changes to the host cell's...
2.
Khasnis S, Veenstra H, McClellan M, Ojeniyi O, Wood C, West M
Biochem J . 2022 Nov; 479(23):2395-2417. PMID: 36383217
The cancer-associated Epstein-Barr virus (EBV) latently infects and immortalises B lymphocytes. EBV latent membrane protein 2A and EBV-encoded microRNAs are known to manipulate B cell receptor signalling to control cell...
3.
Agnarelli A, Mitchell S, Caalim G, Wood C, Milton-Harris L, Chevassut T, et al.
Hematol Oncol . 2022 May; 40(3):417-429. PMID: 35544413
B-cell progenitor fate determinant interferon regulatory factor 4 (IRF4) exerts key roles in the pathogenesis and progression of multiple myeloma (MM), a currently incurable plasma cell malignancy. Aberrant expression of...
4.
Ponnusamy R, Khatri R, Correia P, Wood C, Mancini E, Farrell P, et al.
PLoS Pathog . 2019 Jul; 15(7):e1007458. PMID: 31283782
Natural variation separates Epstein-Barr virus (EBV) into type 1 and type 2 strains. Type 2 EBV is less transforming in vitro due to sequence differences in the EBV transcription factor...
5.
Wood C, Carvell T, Gunnell A, Ojeniyi O, Osborne C, West M
J Virol . 2019 Jan; 93(3). PMID: 30655383
No abstract available.
6.
Pentland I, Campos-Leon K, Cotic M, Davies K, Wood C, Groves I, et al.
PLoS Biol . 2018 Oct; 16(10):e2005752. PMID: 30359362
The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted. Upon epithelial differentiation, E6/E7 transcription...
7.
Wood C, Carvell T, Gunnell A, Ojeniyi O, Osborne C, West M
J Virol . 2018 Jul; 92(19). PMID: 30021904
The oncogenic microRNA (miRNA) miR-155 is the most frequently upregulated miRNA in Epstein-Barr virus (EBV)-positive B cell malignancies and is upregulated in other nonviral lymphomas. Both EBV nuclear antigen 2...
8.
Brocard M, Khasnis S, Wood C, Shannon-Lowe C, West M
Nucleic Acids Res . 2018 Feb; 46(7):3707-3725. PMID: 29385536
Response gene to complement-32 (RGC-32) activates cyclin-dependent kinase 1, regulates the cell cycle and is deregulated in many human tumours. We previously showed that RGC-32 expression is upregulated by the...
9.
Wood C, Veenstra H, Khasnis S, Gunnell A, Webb H, Shannon-Lowe C, et al.
Elife . 2016 Aug; 5. PMID: 27490482
Lymphomagenesis in the presence of deregulated MYC requires suppression of MYC-driven apoptosis, often through downregulation of the pro-apoptotic BCL2L11 gene (Bim). Transcription factors (EBNAs) encoded by the lymphoma-associated Epstein-Barr virus...
10.
Gunnell A, Webb H, Wood C, McClellan M, Wichaidit B, Kempkes B, et al.
Nucleic Acids Res . 2016 Feb; 44(10):4636-50. PMID: 26883634
In B cells infected by the cancer-associated Epstein-Barr virus (EBV), RUNX3 and RUNX1 transcription is manipulated to control cell growth. The EBV-encoded EBNA2 transcription factor (TF) activates RUNX3 transcription leading...