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C D Stubbs

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Articles 53
Citations 892
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Recent Articles
1.
Stubbs C, Ho C, Slater S
J Fluoresc . 2013 Nov; 5(1):19-28. PMID: 24226608
Fluorescence spectroscopy can be used as a highly sensitive and localized probe for hydration in lipid bilayers. Water associates with the head-group region, where it participates in an interlipid network...
2.
Ho C, Slater S, Stagliano B, Stubbs C
Biochemistry . 2001 Aug; 40(34):10334-41. PMID: 11513612
The activity of membrane-associated protein kinase C (PKC) is tightly controlled by the physical properties of the membrane lipid bilayer, in particular, curvature stress, which is induced by bilayer-destabilizing lipid...
3.
Slater S, Seiz J, Stagliano B, Cook A, Milano S, Ho C, et al.
Biochemistry . 2001 May; 40(20):6085-92. PMID: 11352745
Phorbol ester-induced conventional protein kinase C (PKCalpha, -betaIota/IotaIota, and -gamma) isozyme activities are potentiated by 1,2-diacyl-sn-glycerol. This has been attributed to a "cooperative" interaction of the two activators with two...
4.
Slater S, Stagliano B, Seiz J, Curry J, Milano S, Gergich K, et al.
Biochim Biophys Acta . 2001 May; 1544(1-2):207-16. PMID: 11341930
Protein kinase C (PKC) can be activated by interaction with filamentous actin (F-actin) in the absence of membrane lipids (S.J. Slater, S.K. Milano, B.A. Stagliano, K.J. Gergich, J.P. Curry, F.J....
5.
Slater S, Seiz J, Stagliano B, Stubbs C
Biochemistry . 2001 Apr; 40(14):4437-45. PMID: 11284700
Evidence is provided for direct protein-protein interactions between protein kinase C (PKC) alpha, betaI, betaII, gamma, delta, epsilon, and zeta and members of the Rho family of small GTPases. Previous...
6.
Slater S, Milano S, Stagliano B, Gergich K, Curry J, Taddeo F, et al.
Biochemistry . 2000 Jan; 39(2):271-80. PMID: 10630986
The mechanism of activation of protein kinase C isoforms by filamentous actin (F-actin) was investigated with respect to isozyme specificity and phorbol ester and Ca(2+) dependencies. It was found that...
7.
Ho C, Slater S, Stagliano B, Stubbs C
Biochem J . 1999 Nov; 344 Pt 2:451-60. PMID: 10567228
The fluorescent phorbol ester 12-N-methylanthraniloylphorbol 13-acetate [sapintoxin D (SAPD)] was used as both the activator and the probe for the activating conformational change of the C1 domain of recombinant protein...
8.
Stubbs C, Slater S
Alcohol Clin Exp Res . 1999 Oct; 23(9):1552-60. PMID: 10512323
Protein kinase C (PKC) is involved in the control of many key signaling pathways in cells. Investigations over the past decade have shown that many effects of ethanol on cell...
9.
Slater S, Milano S, Stagliano B, Gergich K, Ho C, Mazurek A, et al.
Biochemistry . 1999 Mar; 38(12):3804-15. PMID: 10090770
Protein kinase Calpha (PKCalpha) has been shown to contain two discrete activator sites with differing binding affinities for phorbol esters and diacylglycerols. The interaction of diacylglycerol with a low-affinity phorbol...
10.
Slater S, Taddeo F, Mazurek A, Stagliano B, Milano S, Kelly M, et al.
J Biol Chem . 1998 Aug; 273(36):23160-8. PMID: 9722545
The activity of membrane-associated protein kinase C (PKC) has previously been shown to be regulated by two discrete high and low affinity binding regions for diacylglycerols and phorbol esters (Slater,...