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C D Stretton

Explore the profile of C D Stretton including associated specialties, affiliations and a list of published articles. Areas
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1.
Belvisi M, Stretton C, Miura M, Verleden G, Tadjkarimi S, Yacoub M, et al.
J Appl Physiol (1985) . 1992 Dec; 73(6):2505-10. PMID: 1362724
Inhibitory nonadrenergic noncholinergic (i-NANC) nerves are the only neural bronchodilator pathway in human airways. Possible candidates for the neurotransmitter include vasoactive intestinal peptide (VIP) and nitric oxide (NO) and purines...
2.
Miura M, Belvisi M, Stretton C, Yacoub M, Barnes P
J Physiol . 1992 Sep; 455:1-15. PMID: 1282927
1. Several agonists modulate cholinergic neurotransmission in airways raising the possibility that there may be a common inhibitory mechanism, such as the activation of a common K+ channel in the...
3.
Miura M, Belvisi M, Stretton C, Yacoub M, Barnes P
Am Rev Respir Dis . 1992 Jul; 146(1):132-6. PMID: 1378252
The plasma membrane of airway smooth muscle contains a high density of K+ channels of various types that mainly regulate membrane potential. To examine whether these K+ channels are involved...
4.
Belvisi M, Stretton C, Verleden G, Ledingham S, Yacoub M, Barnes P
J Appl Physiol (1985) . 1992 Mar; 72(3):1096-100. PMID: 1314798
Opioids reduce the cholinergic responses to electrical field stimulation (EFS) in guinea pig and canine airways by a prejunctional effect. We determined whether a similar effect operates in human airways...
5.
Belvisi M, Stretton C, Yacoub M, Barnes P
Eur J Pharmacol . 1992 Jan; 210(2):221-2. PMID: 1350993
In human airways, there is a prominent neural bronchodilator mechanism which is non-adrenergic. In human tracheal segments, we have demonstrated that this response is mediated entirely by nitric oxide (NO),...
6.
Pertwee R, Browne S, Ross T, Stretton C
Pharmacol Biochem Behav . 1991 Nov; 40(3):581-5. PMID: 1666920
Experiments were performed with mice to determine whether doses of the benzodiazepine, flurazepam, or the GABA uptake inhibitor, NO-328, known to potentiate catalepsy induced by delta-9-tetrahydrocannabinol (THC), would also interact...
7.
Belvisi M, Stretton C, Barnes P
J Pharmacol Exp Ther . 1991 Jul; 258(1):36-41. PMID: 2072308
Bombesin is a potent bronchoconstrictor in guinea pigs in vivo, but the mechanisms of its effect are not certain. In vivo increases in tracheal pressure induced by bombesin were measured...
8.
Stretton C, Belvisi M, Barnes P
Neuropeptides . 1991 Mar; 18(3):149-57. PMID: 1712431
Vasoactive intestinal peptide (VIP) is localised to cholinergic nerves in airways. We have investigated the effects of VIP on both cholinergic and non-adrenergic, non-cholinergic (NANC) neuronal bronchoconstrictor responses to electrical...
9.
Verleden G, Belvisi M, Stretton C, Barnes P
Am Rev Respir Dis . 1991 Jan; 143(1):114-8. PMID: 1702590
Nonadrenergic, noncholinergic (NANC) neural bronchoconstrictor responses in guinea pig airways are due to the release of tachykinins from sensory nerves. We have performed an in vitro study using electrical field...
10.
Stretton C, Belvisi M, Barnes P
Neuropeptides . 1990 Dec; 17(4):163-70. PMID: 1709479
Non-adrenergic, non-cholinergic (NANC) neural mechanisms regulate airway tone in guinea-pigs, and it is possible that they may be regulated by other nerves. We have investigated effects of neuropeptide Y (NPY),...