C Csortos
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Explore the profile of C Csortos including associated specialties, affiliations and a list of published articles.
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15
Citations
302
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Recent Articles
1.
Csortos C, Lazar V, Garcia J
Methods Mol Med
. 2011 Feb;
30:59-72.
PMID: 21341016
The purpose of screening cDNA libraries is to isolate a particular cDNA clone encoding a mRNA and by implication, a protein, of interest. The screening is based on identification of...
2.
Birukov K, Csortos C, Marzilli L, Dudek S, Ma S, Bresnick A, et al.
J Biol Chem
. 2000 Dec;
276(11):8567-73.
PMID: 11113114
The Ca(2+)/calmodulin-dependent endothelial cell myosin light chain kinase (MLCK) triggers actomyosin contraction essential for vascular barrier regulation and leukocyte diapedesis. Two high molecular weight MLCK splice variants, EC MLCK-1 and...
3.
Verin A, Csortos C, Durbin S, Aydanyan A, Wang P, PATTERSON C, et al.
J Cell Biochem
. 2000 Jul;
79(1):113-25.
PMID: 10906760
We have previously demonstrated the direct involvement of a type 1 Ser/Thr phosphatase (PPase 1) in endothelial cell (EC) barrier regulation [Am. J. Physiol. 269:L99-L108, 1995]. To further extend this...
4.
Garcia J, Verin A, Schaphorst K, Siddiqui R, PATTERSON C, Csortos C, et al.
Am J Physiol
. 1999 Jun;
276(6):L989-98.
PMID: 10362724
Inflammatory diseases of the lung are characterized by increases in vascular permeability and enhanced leukocyte infiltration, reflecting compromise of the endothelial cell (EC) barrier. We examined potential molecular mechanisms that...
5.
Csortos C, Zolnierowicz S, Bako E, Durbin S, DePaoli-Roach A
J Biol Chem
. 1996 Feb;
271(5):2578-88.
PMID: 8576224
Association of the catalytic subunit (C2) with a variety of regulatory subunits is believed to modulate the activity and specificity of protein phosphatase 2A (PP2A). In this study we report...
6.
Pitcher J, Payne E, Csortos C, DePaoli-Roach A, Lefkowitz R
Proc Natl Acad Sci U S A
. 1995 Aug;
92(18):8343-7.
PMID: 7667292
Phosphorylation of G-protein-coupled receptors plays an important role in regulating their function. In this study the G-protein-coupled receptor phosphatase (GRP) capable of dephosphorylating G-protein-coupled receptor kinase-phosphorylated receptors is described. The...
7.
Zolnierowicz S, Csortos C, Bondor J, Verin A, Mumby M, DePaoli-Roach A
Biochemistry
. 1994 Oct;
33(39):11858-67.
PMID: 7918404
The physiological role of type 2A protein phosphatases (PP2A) is dependent upon the association of the catalytic subunit with a variety of regulatory subunits. In order to understand the function...
8.
DePaoli-Roach A, Park I, Cerovsky V, Csortos C, Durbin S, Kuntz M, et al.
Adv Enzyme Regul
. 1994 Jan;
34:199-224.
PMID: 7942275
Reversible protein phosphorylation is a fundamental mechanism by which many biological functions are regulated. Achievement of such control requires the coordinated action of the interconverting enzymes, the protein kinases and...
9.
Erdodi F, Csortos C, Sparks L, Muranyi A, Gergely P
Arch Biochem Biophys
. 1992 Nov;
298(2):682-7.
PMID: 1329665
The catalytic subunits of bovine platelet protein phosphatases were separated into three distinct forms by chromatography on heparin-Sepharose. Each phosphatase was further purified to apparent homogeneity as judged in sodium...
10.
Csortos C, Matko J, Erdodi F, Gergely P
Biochem Biophys Res Commun
. 1990 Jun;
169(2):559-64.
PMID: 2162668
The catalytic subunits of protein phosphatase-1 and 2A were covalently modified in their reactive sulfhydryl groups with N-(3-Pyrene) maleimide resulting in fluorescent labeling of the proteins to an extent of...