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C C Muller-Goymann

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Articles 54
Citations 490
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Recent Articles
1.
Hinkel S, Mattern K, Dietzel A, Reichl S, Muller-Goymann C
Int J Pharm . 2019 Jun; 566:434-444. PMID: 31163193
In brain research, the hCMEC/D3 cell line is widely used for the establishment of a human in vitro blood-brain barrier (BBB) model. However, its barrier integrity seems to be insufficient...
2.
Fuller J, Kellner T, Gaid M, Beerhues L, Muller-Goymann C
Eur J Pharm Biopharm . 2017 Sep; 126:115-122. PMID: 28870756
Due to the limited chemical stability of the natural hyperforin molecule, a more stable form of hyperforin, i.e., the hyperforin dicyclohexylammonium salt (HYP-DCHA) has been used for ex vivo and...
3.
Fuller J, Muller-Goymann C
Eur J Pharm Biopharm . 2017 Mar; 126:108-114. PMID: 28288835
Hyperforin (HYP), one of the main bioactive compounds in extracts of Hypericum perforatum, is a potential drug candidate for the treatment of skin diseases. Since extracts have proven to support...
4.
Pretor S, Bartels J, Lorenz T, Dahl K, Finke J, Peterat G, et al.
Mol Pharm . 2014 Nov; 12(1):34-45. PMID: 25412253
Unlabelled: In vitro studies of ocular bioavailability of active pharmaceutical ingredients (API) from colloidal drug delivery systems do not consider physiological shear stress generated by eyelid wiping and tear flow....
5.
Paranjpe M, Finke J, Richter C, Gothsch T, Kwade A, Buttgenbach S, et al.
Int J Pharm . 2014 Sep; 476(1-2):41-9. PMID: 25261709
For the development of any colloidal system, thorough characterization is extremely essential. This article discusses the physicochemical characterization of sildenafil-loaded solid lipid nanoparticle dispersions (SLN) including stability analysis over 6...
6.
Paepenmuller T, Muller-Goymann C
Int J Pharm . 2014 Aug; 475(1-2):138-46. PMID: 25107288
Quil A is the purified saponin fraction extracted from the bark of Quillaja saponaria Molina. Besides its utilisation as a surfactant, it is commonly used in a pseudo-ternary system with...
7.
Chinaeke E, Chime S, Ogbonna J, Attama A, Muller-Goymann C, Okore V
J Microencapsul . 2014 Aug; 31(8):796-804. PMID: 25090593
Objectives: To formulate and evaluate artesunate-loaded lipospheres and study the in vitro-in vivo correlations (IV-IVC). Materials And Methods: Lipospheres were formulated by melt homogenisation using structured lipid matrices consisting of...
8.
Kolditz F, Krausze J, Heinz D, Niemann H, Muller-Goymann C
Eur J Pharm Biopharm . 2013 Oct; 86(2):277-83. PMID: 24140590
A constitutively dimeric truncated variant of internalin B (InlB321-CD), acting as stimulator of the receptor tyrosine kinase MET, was tested for dermal wound-healing potential. Due to a lack of the...
9.
Paranjpe M, Neuhaus V, Finke J, Richter C, Gothsch T, Kwade A, et al.
Inhal Toxicol . 2013 Aug; 25(9):536-43. PMID: 23905970
The aim of this study was to investigate the potential cytotoxicity of solid lipid nanoparticles (SLN) loaded with sildenafil. The SLNs were tested as a new drug delivery system (DDS)...
10.
Husch J, Dutagaci B, Glaubitz C, Geppert T, Schneider G, Harms M, et al.
Eur J Pharm Sci . 2011 Jul; 44(1-2):103-16. PMID: 21726639
So-called NSAID-phospholipid-complexes have been recently reported in literature to reduce local gastrointestinal toxicity. The present work was dedicated to the structural characterization of so-called drug-phospholipid-complexes on the example of diclofenac...