C Baldes
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Explore the profile of C Baldes including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
43
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Recent Articles
1.
Taetz S, Nafee N, Beisner J, Piotrowska K, Baldes C, Murdter T, et al.
Eur J Pharm Biopharm
. 2008 Aug;
72(2):358-69.
PMID: 18703137
Tailorable cationic chitosan/PLGA nanoparticles (CPNP) were used for the delivery of an antisense 2'-O-methyl-RNA (2OMR) directed against RNA template of human telomerase. Here, we describe the influence of the chitosan...
2.
Taetz S, Murdter T, Zapp J, Boettcher S, Baldes C, Kleideiter E, et al.
Int J Pharm
. 2008 Mar;
357(1-2):6-14.
PMID: 18313869
The stability of the acridine-based telomere-targeting agent BRACO19, a G-quadruplex stabilizing substance, was tested at different pH, temperature and in different dissolution media. Analysis was performed by HPLC. Decomposition products...
3.
Taetz S, Baldes C, Murdter T, Kleideiter E, Piotrowska K, Bock U, et al.
Pharm Res
. 2006 May;
23(5):1031-7.
PMID: 16715394
Purpose: To characterize the telomerase inhibitor and G-quadruplex stabilizing substance 9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis (3-pyrrolodino-propionamido) acridine x 3HCl (BRACO19) in terms of biopharmaceutical properties such as solubility, protein binding, interaction with membrane lipids,...
4.
Baldes C, Koenig P, Neumann D, Lenhof H, Kohlbacher O, Lehr C
Eur J Pharm Biopharm
. 2005 Sep;
62(1):39-43.
PMID: 16129589
The organic anion transporting protein 1B3 (OATP1B3), formerly termed OATP8, is responsible for uptake and subsequent elimination of multiple amphipathic drugs by the liver. In silico methods for the prediction...