C-M Lehr
Overview
Explore the profile of C-M Lehr including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
358
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0
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Recent Articles
1.
Barthold S, Kletting S, Taffner J, de Souza Carvalho-Wodarz C, Lepeltier E, Loretz B, et al.
J Mater Chem B
. 2020 Apr;
4(13):2377-2386.
PMID: 32263233
Proteins and peptides represent a large fraction of the compounds currently in drug development pipelines. Their application however often depends on the use of carrier systems. Nanoparticles (NPs) are widely...
2.
Dandekar P, Jain R, Keil M, Loretz B, Koch M, Wenz G, et al.
J Mater Chem B
. 2020 Apr;
3(13):2590-2598.
PMID: 32262906
Ideal cationic polymers for siRNA delivery could result in its enhanced cellular internalization, escape from endosomal degradation, and rapid release in cell cytoplasm, to facilitate knockdown of the target gene....
3.
Vogt T, Thomas C, Reichrath J, Schilling L, Mawlood D, Christmann R, et al.
Hautarzt
. 2018 Jan;
69(2):134-142.
PMID: 29362834
Postmenopausal lichen planopilaris (PLPP), also known as fibrosing frontotemporal alopecia Kossard (FFAK), is a not uncommon inflammatory scalp disease affecting approximately 5% of patients at specialized hair centers. The overall...
4.
Mathes C, Melero A, Conrad P, Vogt T, Rigo L, Selzer D, et al.
J Control Release
. 2015 Dec;
223:207-214.
PMID: 26686081
The treatment of various hair disorders has become a central focus of good dermatologic patient care as it affects men and women all over the world. For many inflammatory-based scalp...
5.
Nafee N, Hirosue M, Loretz B, Wenz G, Lehr C
Colloids Surf B Biointerfaces
. 2015 Mar;
129:30-8.
PMID: 25819363
A series of cyclodextrin-based star polymers were synthesized using β-cyclodextrin (CD) as hydrophilic core, methyl methacrylate (MMA) and tert-butyl acrylate (tBA) as hydrophobic arms. Star polymers, either homopolymers or random/block...
6.
Ali H, Weigmann B, Neurath M, Collnot E, Windbergs M, Lehr C
J Control Release
. 2014 Apr;
183:167-77.
PMID: 24685705
The purpose of this study was to investigate the therapeutic potential of budesonide loaded nanocarriers for the treatment of inflammatory bowel disease (IBD). First, budesonide was encapsulated in poly(lactic-co-glycolic) acid...
7.
Raber A, Mittal A, Schafer J, Bakowsky U, Reichrath J, Vogt T, et al.
J Control Release
. 2014 Feb;
179:25-32.
PMID: 24486055
Drug delivery via the hair follicle (HF) especially with nanoparticles (NP) recently gained attention due to a depot effect and facilitated absorption conditions within the lower HF. With the prospect...
8.
Windbergs M, Hansen S, Schroeter A, Schaefer U, Lehr C, Bouwstra J
Skin Pharmacol Physiol
. 2013 Aug;
26(4-6):317-30.
PMID: 23921119
This review presents an overview of German and Dutch research institutions and their studies in the field of skin drug delivery and adjacent topics. In the Netherlands, the involved research...
9.
Dong M, Murdter T, Philippi C, Loretz B, Schaefer U, Lehr C, et al.
Eur J Pharm Biopharm
. 2012 May;
81(3):478-85.
PMID: 22565122
Pulmonary delivery of drugs, particularly in the treatment of lung cancer, is an attractive strategy for future targeted therapy. In this context, inhalation of nanoplexes might offer a new mode...
10.
Nafee N, Schneider M, Friebel K, Dong M, Schaefer U, Murdter T, et al.
Eur J Pharm Biopharm
. 2011 Dec;
80(3):478-89.
PMID: 22198416
Antisense oligonucleotide, 2'-O-Methyl-RNA (OMR), is known as potent telomerase inhibitor for the treatment of lung cancer but limited by poor intracellular uptake. Chitosan-coated polymeric nanoparticles were compared to chitosan solution...