C Adrain
Overview
Explore the profile of C Adrain including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
812
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0
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Recent Articles
1.
Taylor R, Adrain C, Martin S
Cell Death Differ
. 2005 Aug;
12(9):1213-7.
PMID: 16094400
No abstract available.
2.
Adrain C, Creagh E, Martin S
EMBO J
. 2001 Dec;
20(23):6627-36.
PMID: 11726499
Smac/DIABLO is a mitochondrial protein that potentiates some forms of apoptosis, possibly by neutralizing one or more members of the IAP family of apoptosis inhibitory proteins. Smac has been shown...
3.
Bouchier-Hayes L, Conroy H, Egan H, Adrain C, Creagh E, MacFarlane M, et al.
J Biol Chem
. 2001 Sep;
276(47):44069-77.
PMID: 11551959
Proteins possessing the caspase recruitment domain (CARD) motif have been implicated in pathways leading to activation of caspases or NF-kappaB in the context of apoptosis or inflammation, respectively. Here we...
4.
5.
Adrain C, Martin S
Trends Biochem Sci
. 2001 Jun;
26(6):390-7.
PMID: 11406413
The caspase family of cysteine proteases have emerged as central regulators of apoptosis. Diverse cellular stresses trigger caspase activation by promoting release of mitochondrial components, including cytochrome c, into the...
6.
Slee E, Adrain C, Martin S
J Biol Chem
. 2000 Nov;
276(10):7320-6.
PMID: 11058599
Apoptosis is orchestrated by a family of cysteine proteases known as the caspases. Fourteen mammalian caspases have been identified, three of which (caspase-3, -6, and -7) are thought to coordinate...
7.
Slee E, Adrain C, Martin S
Cell Death Differ
. 1999 Dec;
6(11):1067-74.
PMID: 10578175
Caspases participate in the molecular control of apoptosis in several guises; as triggers of the death machinery, as regulatory elements within it, and ultimately as a subset of the effector...
8.
Adrain C, Slee E, Harte M, Martin S
J Biol Chem
. 1999 Jul;
274(30):20855-60.
PMID: 10409627
Apoptotic protease activating factor-1 (Apaf-1) has been identified as a proximal activator of caspase-9 in cell death pathways that trigger mitochondrial damage and cytochrome c release. The mechanism of Apaf-1...