C A JAKOB
Overview
Explore the profile of C A JAKOB including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
390
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0
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Recent Articles
1.
JAKOB C, Bodmer D, Spirig U, Battig P, Marcil A, Dignard D, et al.
EMBO Rep
. 2001 May;
2(5):423-30.
PMID: 11375935
Misfolded proteins are recognized in the endoplasmic reticulum (ER), transported back to the cytoplasm and degraded by the proteasome. Processing intermediates of N-linked oligosaccharides on incompletely folded glycoproteins have an...
2.
JAKOB C, Chevet E, Thomas D, Bergeron J
Results Probl Cell Differ
. 2001 Feb;
33:1-17.
PMID: 11190669
No abstract available.
3.
Pelletier M, Marcil A, SEVIGNY G, JAKOB C, Tessier D, Chevet E, et al.
Glycobiology
. 2000 Aug;
10(8):815-27.
PMID: 10929008
Glucosidase II is an ER heterodimeric enzyme that cleaves sequentially the two innermost alpha-1,3-linked glucose residues from N-linked oligosaccharides on nascent glycoproteins. This processing allows the binding and release of...
4.
Chevet E, JAKOB C, Thomas D, Bergeron J
Semin Cell Dev Biol
. 1999 Dec;
10(5):473-80.
PMID: 10597630
The endoplasmic reticulum (ER) is an intracellular compartment devoted to the synthesis, segregation and folding of soluble and membrane secretory proteins. Some mutations in these proteins lead to their incorrect...
5.
Zapun A, JAKOB C, Thomas D, Bergeron J
Structure
. 1999 Sep;
7(8):R173-82.
PMID: 10467145
The endoplasmic reticulum ensures proper folding of secretory proteins. In this review, we summarize and discuss the functions of different classes of folding mediators in the secretory pathway and propose...
6.
Freimoser F, JAKOB C, Aebi M, Tuor U
Appl Environ Microbiol
. 1999 Jul;
65(8):3727-9.
PMID: 10427074
The entomopathogenic fungus Neozygites parvispora (Entomophthorales: Zygomycetes) grows in vitro as irregularly rod-shaped hyphal bodies in a complex medium. In order to simplify the medium composition and determine growth-promoting compounds...
7.
Burda P, JAKOB C, Beinhauer J, Hegemann J, Aebi M
Glycobiology
. 1999 May;
9(6):617-25.
PMID: 10336995
The assembly of the lipid-linked core oligosaccharide Glc3Man9GlcNAc2, the substrate for N-linked glycosylation of proteins in the endoplasmic reticulum (ER), is catalyzed by different glycosyltransferases located at the membrane of...
8.
JAKOB C, Guldenschuh I, Hurlimann R, Mullhaupt B, Muller A, Ammann R, et al.
Virchows Arch
. 1999 Mar;
434(1):57-62.
PMID: 10071236
DNA methylation plays an important part in the regulation of gene expression. Alterations in DNA methylation in tumours have been reported and have been used to generate hypotheses about mutagenesis...
9.
JAKOB C, Burda P, Roth J, Aebi M
J Cell Biol
. 1998 Sep;
142(5):1223-33.
PMID: 9732283
In Saccharomyces cerevisiae, transfer of N-linked oligosaccharides is immediately followed by trimming of ER-localized glycosidases. We analyzed the influence of specific oligosaccharide structures for degradation of misfolded carboxypeptidase Y (CPY)....
10.
Shahinian S, Dijkgraaf G, Sdicu A, Thomas D, JAKOB C, Aebi M, et al.
Genetics
. 1998 Jun;
149(2):843-56.
PMID: 9611196
beta-1,6-Glucan plays a key structural role in the yeast cell wall. Of the genes involved in its biosynthesis, the activity of Cwh41p is known, i.e., the glucosidase I enzyme of...