C A Dinarello
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Explore the profile of C A Dinarello including associated specialties, affiliations and a list of published articles.
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636
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24847
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Recent Articles
1.
Badii M, Gaal O, Cleophas M, Kluck V, Davar R, Habibi E, et al.
Arthritis Res Ther
. 2021 Jul;
23(1):202.
PMID: 34321071
Objectives: Hyperuricemia is a metabolic condition central to gout pathogenesis. Urate exposure primes human monocytes towards a higher capacity to produce and release IL-1β. In this study, we assessed the...
2.
Kouwenberg M, Pulskens W, Diepeveen L, Bakker-van Bebber M, Dinarello C, Netea M, et al.
PLoS One
. 2021 May;
16(5):e0251809.
PMID: 34029331
The dendritic cell (DC)-derived cytokine profile contributes to naive T cell differentiation, thereby directing the immune response. IL-37 is a cytokine with anti-inflammatory characteristics that has been demonstrated to induce...
3.
Kanni T, Argyropoulou M, Dinarello C, Simard J, Giamarellos-Bourboulis E
Clin Exp Dermatol
. 2020 Jun;
46(1):162-163.
PMID: 32516832
No abstract available.
4.
Cleophas M, Crisan T, Kluck V, Hoogerbrugge N, Netea-Maier R, Dinarello C, et al.
Arthritis Res Ther
. 2019 Feb;
21(1):50.
PMID: 30728075
Background: Acute gouty arthritis currently is the most common form of inflammatory arthritis in developed countries. Treatment is still suboptimal. Dosage of urate-lowering therapy is often too low to reach...
5.
Zhai Z, Liu W, Kaur M, Luo Y, Domenico J, Samson J, et al.
Oncogene
. 2017 Mar;
36(27):3820-3830.
PMID: 28263976
Inflammasomes are mediators of inflammation, and constitutively activated NLRP3 inflammasomes have been linked to interleukin-1β (IL-1β)-mediated tumorigenesis in human melanoma. Whereas NLRP3 regulation of caspase-1 activation requires the adaptor protein...
6.
Shirey K, Lai W, Patel M, Pletneva L, Pang C, Kurt-Jones E, et al.
Mucosal Immunol
. 2016 Jan;
9(5):1173-82.
PMID: 26813341
We previously reported that TLR4(-/-) mice are refractory to mouse-adapted A/PR/8/34 (PR8) influenza-induced lethality and that therapeutic administration of the TLR4 antagonist Eritoran blocked PR8-induced lethality and acute lung injury...
7.
Lundh M, Christensen D, Damgaard Nielsen M, Richardson S, Dahllof M, Skovgaard T, et al.
Diabetologia
. 2012 Jul;
55(9):2421-31.
PMID: 22772764
Aims/hypothesis: Histone deacetylases (HDACs) are promising pharmacological targets in cancer and autoimmune diseases. All 11 classical HDACs (HDAC1-11) are found in the pancreatic beta cell, and HDAC inhibitors (HDACi) protect...
8.
Keswani A, Chustz R, Suh L, Carter R, Peters A, Tan B, et al.
Allergy
. 2011 Sep;
67(1):25-32.
PMID: 21899560
Background: Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and sinuses and is frequently divided into polypoid CRS (CRSwNP) and nonpolypoid CRS (CRSsNP)....
9.
van de Veerdonk F, Netea M, Dinarello C, van der Meer J
Neth J Med
. 2011 Mar;
69(2):95.
PMID: 21411850
No abstract available.
10.
Dinarello C
J Intern Med
. 2010 Dec;
269(1):16-28.
PMID: 21158974
An expanding spectrum of acute and chronic inflammatory diseases is considered 'autoinflammatory' diseases. This review considers autoinflammatory diseases as being distinct from 'autoimmune' diseases. Autoimmune diseases are associated with dysfunctional...