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C A Austin

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Articles 59
Citations 867
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Recent Articles
1.
Austin C, Rodgers M
J Phys Chem A . 2014 Jul; 118(29):5488-500. PMID: 24977648
Threshold collision-induced dissociation (CID) of alkali metal cation-hexacyclen (ha18C6) complexes, M(+)(ha18C6), with xenon is studied using guided ion beam tandem mass spectrometry techniques. The alkali metal cations examined here include:...
2.
Armentrout P, Austin C, Rodgers M
J Phys Chem A . 2014 Feb; 118(37):8088-97. PMID: 24559535
Quantitative interactions of the alkali metal cations with the cyclic 15-crown-5 polyether ligand (15C5) are studied. In this work, Rb(+)(15C5) and Cs(+)(15C5) complexes are formed using electrospray ionization and studied...
3.
Squirrell D, Kenny J, Mawer N, Gupta M, West J, Currie Z, et al.
Eye (Lond) . 2004 Jun; 19(1):55-9. PMID: 15184957
Aims: 1. To assess the prevalence of visual impairment in those patients who sustain proximal hip fracture after a simple fall. 2. To test the validity of a simple screening...
4.
McKee K, Orbell S, Austin C, Bettridge R, Liddle B, Morgan K, et al.
Disabil Rehabil . 2002 May; 24(6):327-33. PMID: 12017466
Purpose: This study sought to determine whether fear of falling and falls efficacy independently contribute to the prediction of health outcomes after a fall, controlling for length of stay in...
5.
Meczes E, Pearson A, Austin C, Tilby M
Br J Cancer . 2002 Mar; 86(3):485-9. PMID: 11875719
The growth inhibitory effects of cisplatin and etoposide on neuroblastoma cell lines were investigated in several scheduled combinations. Results were analyzed using median effect and combination index analyses. In all...
6.
Johnson C, Padget K, Austin C, Turner B
J Biol Chem . 2001 Jan; 276(7):4539-42. PMID: 11136718
DNA topoisomerase II (topo II) is a ubiquitous nuclear enzyme that is involved in DNA replication, transcription, chromosome segregation, and apoptosis. Here we show by immunoprecipitation, pull down with glutathione...
7.
Padget K, Pearson A, Austin C
Leukemia . 2000 Nov; 14(11):1997-2005. PMID: 11069037
DNA topoisomerase II (topo II) is an essential nuclear enzyme and is the target for etoposide, which is used in the therapy of childhood acute lymphoblastic leukaemia (ALL). Topo II...
8.
Patel S, Jazrawi E, Creighton A, Austin C, Fisher L
Mol Pharmacol . 2000 Aug; 58(3):560-8. PMID: 10953049
Topoisomerase II is an ATP-operated protein clamp that captures a DNA helix and transports it through another DNA duplex, allowing chromosome segregation at mitosis. A number of cytotoxic bisdioxopiperazines such...
9.
Padget K, Stewart A, Charlton P, Tilby M, Austin C
Biochem Pharmacol . 2000 Aug; 60(6):817-21. PMID: 10930536
The antitumour agents DACA (XR5000; N-[2-(dimethylamino)ethyl]acridine-4-carboxamide) and TAS-103 (6-[2-(dimethylamino)ethylamino]-3-hydroxy-7H-indeno[2, 1-c]quinolin-7-one dihydrochloride) have been shown to inhibit two essential nuclear enzymes in vitro, DNA topoisomerase I and DNA topoisomerase (topo) II....
10.
De Martino S, Yan Y, Jowett T, Postlethwait J, Varga Z, Ashworth A, et al.
Dev Dyn . 2000 Mar; 217(3):279-92. PMID: 10741422
To investigate the role of sox genes in vertebrate development, we have isolated sox11 from zebrafish (Danio rerio). Two distinct classes of sox11-related cDNAs were identified, sox11a and sox11b. The...