Byron Burnette
Overview
Explore the profile of Byron Burnette including associated specialties, affiliations and a list of published articles.
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13
Citations
3245
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Recent Articles
1.
Arina A, Beckett M, Fernandez C, Zheng W, Pitroda S, Chmura S, et al.
Nat Commun
. 2019 Sep;
10(1):3959.
PMID: 31477729
Successful combinations of radiotherapy and immunotherapy depend on the presence of live T cells within the tumor; however, radiotherapy is believed to damage T cells. Here, based on longitudinal in...
2.
Zheng W, Skowron K, Namm J, Burnette B, Fernandez C, Arina A, et al.
Oncotarget
. 2016 Jun;
7(28):43039-43051.
PMID: 27343548
The majority of cancer patients respond poorly to either vaccine or checkpoint blockade, and even to the combination of both. They are often resistant to high doses of radiation therapy...
3.
Deng L, Liang H, Xu M, Yang X, Burnette B, Arina A, et al.
Immunity
. 2014 Dec;
41(5):843-52.
PMID: 25517616
Ionizing radiation-mediated tumor regression depends on type I interferon (IFN) and the adaptive immune response, but several pathways control I IFN induction. Here, we demonstrate that adaptor protein STING, but...
4.
Burnette B, Weichselbaum R
Semin Radiat Oncol
. 2014 Dec;
25(1):40-5.
PMID: 25481265
Radiation has been a staple of cancer therapy since the early 20th century and is implemented in nearly half of current cancer treatment plans. Originally, the genotoxic function of radiation...
5.
Deng L, Liang H, Burnette B, Weicheslbaum R, Fu Y
Oncoimmunology
. 2014 Jul;
3:e28499.
PMID: 25050217
Tumor relapse after radiotherapy may be due to the upregulation of programmed cell death ligand 1 (PD-L1). We demonstrated that anti-PD-L1 antibody synergizes with radiation to control local and distal...
6.
Binder D, Engels B, Arina A, Yu P, Slauch J, Fu Y, et al.
Cancer Immunol Res
. 2014 Jan;
1(2):123-33.
PMID: 24455752
Immunogenic tumors grow progressively even when heavily infiltrated by CD8(+) T cells. We investigated how to rescue CD8(+) T cell function in long-established immunogenic melanomas that contained a high percentage...
7.
Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum R, et al.
J Clin Invest
. 2014 Jan;
124(2):687-95.
PMID: 24382348
High-dose ionizing irradiation (IR) results in direct tumor cell death and augments tumor-specific immunity, which enhances tumor control both locally and distantly. Unfortunately, local relapses often occur following IR treatment,...
8.
Liang H, Deng L, Burnette B, Weichselbaum R, Fu Y
Oncoimmunology
. 2013 Dec;
2(9):e25668.
PMID: 24319637
Despite its efficacy and widespread use, radiation therapy is often associated with local or distal tumor relapse. We have recently found that CD8 T cells and their cytokines are essential...
9.
Burnette B, Weichselbaum R
Semin Radiat Oncol
. 2013 Sep;
23(4):273-80.
PMID: 24012341
Radiation therapy is currently one of the most widely utilized treatment strategies in the clinical management of cancer. Classically, radiation therapy was developed as an anticancer treatment on the basis...
10.
Liang H, Deng L, Chmura S, Burnette B, Liadis N, Darga T, et al.
J Immunol
. 2013 May;
190(11):5874-81.
PMID: 23630355
Local failures following radiation therapy are multifactorial, and the contributions of the tumor and the host are complex. Current models of tumor equilibrium suggest that a balance exists between cell...