Bryden A F Le Bailly
Overview
Explore the profile of Bryden A F Le Bailly including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
103
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Recent Articles
1.
Wootten M, Le Bailly B, Tshepelevitsh S, Leito I, Clayden J
Chem Sci
. 2022 Mar;
13(8):2258-2269.
PMID: 35310487
Molecules that change shape in response to environmental conditions are central to biological molecular communication devices and their synthetic chemical analogues. Here we report a molecular system in which a...
2.
Eccles N, Della Sala F, Le Bailly B, Whitehead G, Clayden J, Webb S
ChemistryOpen
. 2020 Mar;
9(3):338-345.
PMID: 32195074
Two α-aminoisobutyric acid (Aib) foldamers bearing Zn(II)-chelating N-termini have been synthesized and compared with a reported Aib foldamer that has a bis(quinolinyl)/mono(pyridyl) cap (BQPA group). Replacement of the quinolinyl arms...
3.
Eccles N, Le Bailly B, Della Sala F, Vitorica-Yrezabal I, Clayden J, Webb S
Chem Commun (Camb)
. 2019 Jul;
55(63):9331-9334.
PMID: 31313773
A crystallographically characterised zinc(ii)-capped foldamer can sense the enantiomeric excess of scalemic carboxylate solutions, including those produced by enantioselective organocatalysis, and can relay this input signal along the foldamer body...
4.
Le Bailly B, Byrne L, Diemer V, Foroozandeh M, Morris G, Clayden J
Chem Sci
. 2018 Jan;
6(4):2313-2322.
PMID: 29308146
Although foldamers, by definition, are extended molecular structures with a well-defined conformation, minor conformers must be populated at least to some extent in solution. We present a quantitative analysis of...
5.
Diemer V, Maury J, Le Bailly B, Webb S, Clayden J
Chem Commun (Camb)
. 2017 Sep;
53(78):10768-10771.
PMID: 28875189
Conformationally mobile oligomers with helical structures, or 'dynamic foldamers', may populate a mixture of screw-sense conformers whose relative proportion has been used as a means of communicating information on a...
6.
Tomsett M, Maffucci I, Le Bailly B, Byrne L, Bijvoets S, Lizio M, et al.
Chem Sci
. 2017 Apr;
8(4):3007-3018.
PMID: 28451368
Helical oligomers of achiral monomers adopt domains of uniform screw sense, which are occasionally interrupted by screw-sense reversals. These rare, elusive, and fast-moving features have eluded detailed characterization. We now...
7.
Le Bailly B, Clayden J
Chem Commun (Camb)
. 2016 Mar;
52(27):4852-63.
PMID: 26955864
Foldamers can be made more than pieces of static, conformationally uniform molecular architecture by designing into their structure the conformational dynamism characteristic of functional molecular machines. We show that these...
8.
Le Bailly B, Byrne L, Clayden J
Angew Chem Int Ed Engl
. 2016 Jan;
55(6):2132-6.
PMID: 26762559
Small changes in the structure of a foldamer may lead to gross changes in conformational preference. We show that the simple insertion or deletion of a single hydrogen bond by...
9.
Maury J, Le Bailly B, Raftery J, Clayden J
Chem Commun (Camb)
. 2015 Jun;
51(59):11802-5.
PMID: 26107614
Linking together an oligourea and an oligoamide foldamer gives rise to a conformationally well-defined structure, despite the different hydrogen-bonding patterns in the two domains, provided the oligomers are ligated amide...
10.
Le Bailly B, Clayden J
Chem Commun (Camb)
. 2014 Jun;
50(59):7949-52.
PMID: 24918692
The global screw-sense preference of an achiral helical oligomer may be controlled by a single chiral monomer located at one terminus. Remarkably, maximal control is induced in oligomers of the...