Bryan T Grenfell
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Explore the profile of Bryan T Grenfell including associated specialties, affiliations and a list of published articles.
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216
Citations
12099
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Recent Articles
1.
Park S, Noble B, Howerton E, Nielsen B, Lentz S, Ambroggio L, et al.
Epidemics
. 2024 Dec;
49:100808.
PMID: 39642758
The introduction of non-pharmaceutical interventions (NPIs) against COVID-19 disrupted circulation of many respiratory pathogens and eventually caused large, delayed outbreaks, owing to the build up of the susceptible pool during...
2.
Madden W, Jin W, Lopman B, Zufle A, Dalziel B, Metcalf C, et al.
PLoS Comput Biol
. 2024 Nov;
20(11):e1012616.
PMID: 39570994
Measles is an important infectious disease system both for its burden on public health and as an opportunity for studying nonlinear spatio-temporal disease dynamics. Traditional mechanistic models often struggle to...
3.
Espinoza B, Saad-Roy C, Grenfell B, Levin S, Marathe M
Proc Biol Sci
. 2024 Oct;
291(2033):20241772.
PMID: 39471851
The multiple immunity responses exhibited in the population and co-circulating variants documented during pandemics show a high potential to generate diverse long-term epidemiological scenarios. Transmission variability, immune uncertainties and human...
4.
Park S, Lawal T, Marin M, Marlow M, Grenfell B, Masters N
Proc Natl Acad Sci U S A
. 2024 Oct;
121(43):e2403808121.
PMID: 39401354
Mumps outbreaks among fully vaccinated young adults have raised questions about potential waning of immunity over time and need for a third dose of the measles, mumps, rubella (MMR) vaccine....
5.
Park S, Cobey S, Metcalf C, Levine J, Grenfell B
Science
. 2024 Oct;
386(6718):175-179.
PMID: 39388572
Observations of pathogen community structure provide evidence for both the coexistence and replacement of related strains. Despite many studies of specific host-pathogen systems, a unifying framework for predicting the outcomes...
6.
Saad-Roy C, Morris S, Boots M, Baker R, Lewis B, Farrar J, et al.
PLoS Comput Biol
. 2024 Aug;
20(8):e1012211.
PMID: 39102402
The SARS-CoV-2 pandemic has generated a considerable number of infections and associated morbidity and mortality across the world. Recovery from these infections, combined with the onset of large-scale vaccination, have...
7.
Nielsen B, Berrig C, Grenfell B, Andreasen V
Theor Popul Biol
. 2024 Aug;
159:25-34.
PMID: 39094981
Leveraging the simplicity of nucleotide mismatch distributions, we provide an intuitive window into the evolution of the human influenza A 'nonstructural' (NS) gene segment. In an analysis suggested by the...
8.
Yang Q, Park S, Saad-Roy C, Ahmad I, Viboud C, Arinaminpathy N, et al.
Epidemics
. 2024 Jun;
48:100776.
PMID: 38944025
Influenza A has two hemagglutinin groups, with stronger cross-immunity to reinfection within than between groups. Here, we explore the implications of this heterogeneity for proposed cross-protective influenza vaccines that may...
9.
Freedman A, Sheen J, Tsai S, Yao J, Lifshitz E, Adinaro D, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(17):e2314357121.
PMID: 38630720
Characterizing the relationship between disease testing behaviors and infectious disease dynamics is of great importance for public health. Tests for both current and past infection can influence disease-related behaviors at...
10.
Sheen J, Rasambainarivo F, Saad-Roy C, Grenfell B, Metcalf C
Nat Commun
. 2024 Jan;
15(1):605.
PMID: 38242897
Theoretical models have successfully predicted the evolution of poultry pathogen virulence in industrialized farm contexts of broiler chicken populations. Whether there are ecological factors specific to more traditional rural farming...