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Bryan Severyn

Explore the profile of Bryan Severyn including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Van Damme E, Vanhove J, Severyn B, Verschueren L, Pauwels F
Front Microbiol . 2021 Oct; 12:724877. PMID: 34603251
Despite the availability of a prophylactic vaccine, chronic hepatitis B (CHB) caused by the hepatitis B virus (HBV) is a major health problem affecting an estimated 292 million people globally....
2.
Severyn B, Nguyen T, Altman M, Li L, Nagashima K, Naumov G, et al.
J Biomol Screen . 2016 Jul; 21(9):989-97. PMID: 27461835
The RAS-MAPK pathway controls many cellular programs, including cell proliferation, differentiation, and apoptosis. In colorectal cancers, recurrent mutations in this pathway often lead to increased cell signaling that may contribute...
3.
Severyn B, Liehr R, Wolicki A, Nguyen K, Hudak E, Ferrer M, et al.
ACS Chem Biol . 2011 Oct; 6(12):1391-8. PMID: 21974780
Combination therapies that enhance efficacy or permit reduced dosages to be administered have seen great success in a variety of therapeutic applications. More fundamentally, the discovery of epistatic pathway interactions...