Bryan M Turner
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Explore the profile of Bryan M Turner including associated specialties, affiliations and a list of published articles.
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52
Citations
2799
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Recent Articles
1.
Breiling A, ONeill L, DEliseo D, Turner B, Orlando V
EMBO Rep
. 2023 Aug;
24(8):e57607.
PMID: 37534582
No abstract available.
2.
Halsall J, Andrews S, Krueger F, Rutledge C, Ficz G, Reik W, et al.
Sci Rep
. 2021 Feb;
11(1):3009.
PMID: 33542322
Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in...
3.
Wiersma M, Bussiere M, Halsall J, Turan N, Slany R, Turner B, et al.
Epigenetics Chromatin
. 2016 Nov;
9:52.
PMID: 27895715
Background: The KMT2A/MLL1 lysine methyltransferase complex is an epigenetic regulator of selected developmental genes, in part through the SET domain-catalysed methylation of H3K4. It is essential for normal embryonic development...
4.
Halsall J, Turner B
Bioessays
. 2016 Oct;
38(11):1102-1110.
PMID: 27717012
Histone deacetylase inhibitors (HDACi) are in clinical trials against a variety of cancers. Despite early successes, results against the more common solid tumors have been mixed. How is it that...
5.
Halsall J, Turan N, Wiersma M, Turner B
Epigenetics Chromatin
. 2015 Sep;
8:29.
PMID: 26380582
Background: The genome-wide hyperacetylation of chromatin caused by histone deacetylase inhibitors (HDACi) is surprisingly well tolerated by most eukaryotic cells. The homeostatic mechanisms that underlie this tolerance are unknown. Here...
6.
Terrenoire E, Halsall J, Turner B
BMC Genet
. 2015 May;
16:44.
PMID: 25925961
Background: Using metaphase spreads from human lymphoblastoid cell lines, we previously showed how immunofluorescence microscopy could define the distribution of histone modifications across metaphase chromosomes. We showed that different histone...
7.
Brockdorff N, Turner B
Cold Spring Harb Perspect Biol
. 2015 Mar;
7(3):a019406.
PMID: 25731764
Many organisms show major chromosomal differences between sexes. In mammals, females have two copies of a large, gene-rich chromosome, the X, whereas males have one X and a small, gene-poor...
8.
Turner B
Biochim Biophys Acta
. 2014 Jan;
1839(8):623-6.
PMID: 24412235
The nucleosome core particle is the first stage of DNA packaging in virtually all eukaryotes. It both organises nuclear DNA and protects it from adventitious binding of transcription factors and...
9.
Boudadi E, Stower H, Halsall J, Rutledge C, Leeb M, Wutz A, et al.
Epigenetics Chromatin
. 2013 May;
6(1):11.
PMID: 23634885
Background: Histone deacetylase inhibitors (HDACi) cause histone hyperacetylation and H3K4 hypermethylation in various cell types. They find clinical application as anti-epileptics and chemotherapeutic agents, but the pathways through which they...
10.
Singh P, Doig C, Dhiman V, Turner B, Smiraglia D, Campbell M
J Steroid Biochem Mol Biol
. 2012 Oct;
136:258-63.
PMID: 23098689
The current study aimed to examine the gene specific mechanisms by which the actions of the vitamin D receptor (VDR) are distorted in prostate cancer. Transcriptional responses toward the VDR...