Bryan J Matthews
Overview
Explore the profile of Bryan J Matthews including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
340
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0
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Recent Articles
1.
Matthews B, Melia T, Waxman D
PLoS Genet
. 2021 Nov;
17(11):e1009588.
PMID: 34752452
Sex differences in gene expression are widespread in the liver, where many autosomal factors act in tandem with growth hormone signaling to regulate individual variability of sex differences in liver...
2.
Matthews B, Waxman D
Epigenetics Chromatin
. 2020 Jul;
13(1):30.
PMID: 32680543
Several thousand sex-differential distal enhancers have been identified in mouse liver; however, their links to sex-biased genes and the impact of any sex-differences in nuclear organization and chromatin interactions are...
3.
Matthews B, Waxman D
Elife
. 2018 May;
7.
PMID: 29757144
CTCF and cohesin are key drivers of 3D-nuclear organization, anchoring the megabase-scale Topologically Associating Domains (TADs) that segment the genome. Here, we present and validate a computational method to predict...
4.
Soltis A, Kennedy N, Xin X, Zhou F, Ficarro S, Yap Y, et al.
Cell Rep
. 2017 Dec;
21(11):3317-3328.
PMID: 29241556
Obesity is a major human health crisis that promotes insulin resistance and, ultimately, type 2 diabetes. The molecular mechanisms that mediate this response occur across many highly complex biological regulatory...
5.
Brennan J, Messerschmidt J, Williams L, Matthews B, Reynoso M, Gilmore T
Proc Natl Acad Sci U S A
. 2017 Nov;
114(47):E10122-E10131.
PMID: 29109290
In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream pathways, specifically those that direct expression of innate immune effector genes. TLRs also have...
6.
Soltis A, Motola S, Vernia S, Ng C, Kennedy N, Dalin S, et al.
Sci Rep
. 2017 Mar;
7(1):174.
PMID: 28282965
Diet plays a crucial role in shaping human health and disease. Diets promoting obesity and insulin resistance can lead to severe metabolic diseases, while calorie-restricted (CR) diets can improve health...
7.
Moore P, Matthews B, Chiu D, Chandra A, Quiram P
Retina
. 2016 Jul;
36(8):1609-10.
PMID: 27456025
No abstract available.
8.
Cheng N, Chandra A, Roufail E, Moodie J, Yeoh J, Allen P, et al.
Retin Cases Brief Rep
. 2016 Feb;
11(1):30-33.
PMID: 26866434
Purpose: To describe the novel use of a chorioretinal biopsy technique to confirm the microbiological diagnosis of endogenous Escherichia coli (E. coli) endophthalmitis, when other investigations have been proven nondiagnostic....
9.
Gosline S, Gurtan A, JnBaptiste C, Bosson A, Milani P, Dalin S, et al.
Cell Rep
. 2016 Jan;
14(2):310-9.
PMID: 26748710
MicroRNAs (miRNAs) regulate diverse biological processes by repressing mRNAs, but their modest effects on direct targets, together with their participation in larger regulatory networks, make it challenging to delineate miRNA-mediated...
10.
Matthews B, Partridge D, Sheard R, Rennie I, Mudhar H
Indian J Ophthalmol
. 2014 Jan;
61(12):763-5.
PMID: 24413827
A 67-year-old former gold miner with rheumatoid arthritis, treated with steroids and methotrexate, presented to eye casualty with a painful right eye. Examination revealed an anterior uveitis and despite an...