Bryan D Maliken
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Explore the profile of Bryan D Maliken including associated specialties, affiliations and a list of published articles.
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19
Citations
1307
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Recent Articles
11.
Handa P, Vemulakonda A, Maliken B, Morgan-Stevenson V, Nelson J, Dhillon B, et al.
Ann Hepatol
. 2017 Jan;
16(1):77-85.
PMID: 28051796
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. We have previously shown that hepatic reticuloendothelial system (RES) iron deposition is associated with an...
12.
Kanisicak O, Khalil H, Ivey M, Karch J, Maliken B, Correll R, et al.
Nat Commun
. 2016 Jul;
7:12260.
PMID: 27447449
Cardiac fibroblasts convert to myofibroblasts with injury to mediate healing after acute myocardial infarction (MI) and to mediate long-standing fibrosis with chronic disease. Myofibroblasts remain a poorly defined cell type...
13.
Handa P, Morgan-Stevenson V, Maliken B, Nelson J, Washington S, Westerman M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2015 Nov;
310(2):G117-27.
PMID: 26564716
The aim of this study was to determine the effect of iron overload in the development of nonalcoholic steatohepatitis (NASH) in a genetically obese mouse model (Lepr(db/db)). Leptin receptor-deficient mice...
14.
Brody M, Schips T, Vanhoutte D, Kanisicak O, Karch J, Maliken B, et al.
Mol Cell Biol
. 2015 Oct;
36(1):2-12.
PMID: 26459760
Thrombospondins are a family of stress-inducible secreted glycoproteins that underlie tissue remodeling. We recently reported that thrombospondin-4 (Thbs4) has a critical intracellular function, regulating the adaptive endoplasmic reticulum (ER) stress...
15.
Handa P, Maliken B, Nelson J, Morgan-Stevenson V, Messner D, Dhillon B, et al.
Hepatology
. 2014 Jan;
60(1):133-45.
PMID: 24464605
Unlabelled: Obesity and adiponectin depletion have been associated with the occurrence of nonalcoholic fatty liver disease (NAFLD). The goal of this study was to identify the relationship between weight gain,...
16.
Maliken B, Nelson J, Klintworth H, Beauchamp M, Yeh M, Kowdley K
Hepatology
. 2013 Jan;
57(5):1806-13.
PMID: 23325576
Unlabelled: The aim of this study was to examine the relationship between the presence of hepatic iron deposition, apoptosis, histologic features, and serum markers of oxidative stress (OS) and cell...
17.
Shawki A, Knight P, Maliken B, Niespodzany E, Mackenzie B
Curr Top Membr
. 2012 Nov;
70:169-214.
PMID: 23177986
Divalent metal-ion transporter-1 (DMT1) is a widely expressed, iron-preferring membrane transport protein. Animal models establish that DMT1 plays indispensable roles in intestinal nonheme-iron absorption and iron acquisition by erythroid precursor...
18.
Maliken B, Avrin W, Nelson J, Mooney J, Kumar S, Kowdley K
Ann Hepatol
. 2011 Dec;
11(1):77-84.
PMID: 22166564
Background: There is an ongoing clinical need for novel methods to measure hepatic iron content (HIC) noninvasively. Both magnetic resonance imaging (MRI) and superconducting quantum interference device (SQUID) methods have...
19.
Maliken B, Nelson J, Kowdley K
Hepatology
. 2011 Apr;
53(5):1764-6.
PMID: 21520181
Hepcidin is a peptide hormone that regulates iron homeostasis and acts as an antimicrobial peptide. It is expressed and secreted by a variety of cell types in response to iron...