Bryan C Dickinson
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Explore the profile of Bryan C Dickinson including associated specialties, affiliations and a list of published articles.
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105
Citations
3570
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Recent Articles
1.
Qiu T, Azizi S, Pani S, Dickinson B
Cell Chem Biol
. 2025 Feb;
PMID: 40010334
Peroxiredoxins (PRDXs) are a highly conserved family of peroxidases that serve as the primary scavengers of peroxides. Post-translational modifications play crucial roles modulating PRDX activities, tuning the balance between reactive...
2.
Styles M, Pixley J, Wei T, Basile C, Basile C, Lu S, et al.
bioRxiv
. 2025 Jan;
PMID: 39829796
Proteins that selectively bind to a target of interest are foundational components of research pipelines, diagnostics, and therapeutics. Current immunization-based, display-based, and computational approaches for discovering binders are laborious and...
3.
Lan T, Peng C, Yao X, Chan R, Wei T, Rupanya A, et al.
J Am Chem Soc
. 2024 Aug;
146(34):24053-24060.
PMID: 39136646
Macrocyclic peptides are promising scaffolds for the covalent ligand discovery. However, platforms enabling the direct identification of covalent macrocyclic ligands in a high-throughput manner are limited. In this study, we...
4.
Liu Z, Li S, Wang C, Vidmar K, Bracey S, Li L, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(29):e2400883121.
PMID: 38980908
Gasdermin D (GSDMD)-mediated pyroptotic cell death drives inflammatory cytokine release and downstream immune responses upon inflammasome activation, which play important roles in host defense and inflammatory disorders. Upon activation by...
5.
Lan T, Slezak T, Pu J, Zinkus-Boltz J, Adhikari S, Pekow J, et al.
ACS Chem Biol
. 2024 Jun;
19(6):1250-1259.
PMID: 38843544
Calprotectin, a metal ion-binding protein complex, plays a crucial role in the innate immune system and has gained prominence as a biomarker for various intestinal and systemic inflammatory and infectious...
6.
7.
Di M, Lv J, Jing Z, Yang Y, Yan K, Wu J, et al.
Mol Ther Nucleic Acids
. 2024 May;
35(2):102190.
PMID: 38721279
RNA base editors should ideally be free of immunogenicity, compact, efficient, and specific, which has not been achieved for C > U editing. Here we first describe a compact C ...
8.
Pani S, Qiu T, Kentala K, Azizi S, Dickinson B
Nat Chem
. 2024 Apr;
16(5):717-726.
PMID: 38594368
RNA localization is highly regulated, with subcellular organization driving context-dependent cell physiology. Although proximity-based labelling technologies that use highly reactive radicals or carbenes provide a powerful method for unbiased mapping...
9.
S Mesquita F, Abrami L, Linder M, Bamji S, Dickinson B, van der Goot F
Nat Rev Mol Cell Biol
. 2024 Feb;
25(6):488-509.
PMID: 38355760
Over the past two decades, protein S-acylation (often referred to as S-palmitoylation) has emerged as an important regulator of vital signalling pathways. S-Acylation is a reversible post-translational modification that involves...
10.
Liau W, Zhao Q, Bademosi A, Gormal R, Gong H, Marshall P, et al.
Nat Commun
. 2023 Nov;
14(1):7616.
PMID: 37993455
Long noncoding RNAs (lncRNAs) represent a multidimensional class of regulatory molecules that are involved in many aspects of brain function. Emerging evidence indicates that lncRNAs are localized to the synapse;...