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Bryan A McLendon

Explore the profile of Bryan A McLendon including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 76
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Recent Articles
1.
Johnson G, Bazer F, Burghardt R, Wu G, Seo H, Kramer A, et al.
Anim Reprod . 2022 Oct; 15(Suppl 1):843-855. PMID: 36249852
The establishment of pregnancy in sheep includes elongation of the blastocyst into a filamentous conceptus, pregnancy recognition, production of histotroph, attachment of the conceptus to the endometrium for implantation, and...
2.
Moses R, Halloran K, Stenhouse C, Sah N, Kramer A, McLendon B, et al.
Biol Reprod . 2022 Jul; 107(4):1084-1096. PMID: 35835585
Roles of fructose in elongating ovine conceptuses are poorly understood, despite it being the major hexose sugar in fetal fluids and plasma throughout gestation. Therefore, we determined if elongating ovine...
3.
McLendon B, Kramer A, Seo H, Burghardt R, Bazer F, Wu G, et al.
Placenta . 2022 May; 124:28-36. PMID: 35605542
Introduction: The uterus and placenta transport water during pregnancy recognition signaling, conceptus implantation, and placental development/placentation. This is likely influenced by aquaporins (AQPs) in the reproductive tract. This study determined...
4.
Seo H, Kramer A, McLendon B, Cain J, Burghardt R, Wu G, et al.
Biol Reprod . 2022 May; 107(3):823-833. PMID: 35552608
During the peri-implantation period of pregnancy, the trophectoderm of pig conceptuses utilize glucose via multiple biosynthetic pathways to support elongation and implantation, resulting in limited availability of pyruvate for metabolism...
5.
Wu G, Li X, Seo H, McLendon B, Kramer A, Bazer F, et al.
Front Biosci (Landmark Ed) . 2022 Apr; 27(4):117. PMID: 35468676
Background: Fetal-placental development depends on a continuous and efficient supply of nutrients from maternal blood that are acquired by exchange through the placenta. However, the placenta is a low permeability...
6.
Johnson G, Seo H, Bazer F, Wu G, Kramer A, McLendon B, et al.
Mol Reprod Dev . 2022 Apr; 90(7):673-683. PMID: 35460118
Conceptus elongation and early placentation involve growth and remodeling that requires proliferation and migration of cells. This demands conceptuses expend energy before establishment of a placenta connection and when they...
7.
McLendon B, Kramer A, Seo H, Bazer F, Burghardt R, Johnson G
Biology (Basel) . 2021 Jul; 10(6). PMID: 34201059
Cells respond to extracellular mechanical forces through the assembly of integrin adhesion complexes (IACs) that provide a scaffold through which cells sense and transduce responses to those forces. IACs are...
8.
Kramer A, Erikson D, McLendon B, Seo H, Hayashi K, Spencer T, et al.
Biol Reprod . 2021 Jun; 105(4):892-904. PMID: 34165144
Secreted phosphoprotein 1 (SPP1, also known as osteopontin) binds integrins to mediate cell-cell and cell-extracellular matrix communication to promote cell adhesion, migration, and differentiation. Considerable evidence links SPP1 to pregnancy...
9.
Seo H, Johnson G, Bazer F, Wu G, McLendon B, Kramer A
Adv Exp Med Biol . 2021 Mar; 1285:17-28. PMID: 33770400
During the peri-implantation period, conceptuses [embryo and placental membranes, particularly the trophectoderm (Tr)] of farm animals (e.g., sheep and pigs) rapidly elongate from spherical to tubular to filamentous forms. In...
10.
McLendon B, Seo H, Kramer A, Burghardt R, Bazer F, Johnson G
Biol Reprod . 2020 Jul; 103(5):1018-1029. PMID: 32716497
The emerging paradigm in the immunology of pregnancy is that implantation of conceptuses does not progress in an immunologically suppressed environment. Rather, the endometrium undergoes a controlled inflammatory response during...