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Bruno Solano de Freitas Souza

Explore the profile of Bruno Solano de Freitas Souza including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 1069
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Recent Articles
1.
Costa-Ferro Z, Cunha R, Rossi E, Loiola E, Cipriano B, Figueiredo J, et al.
Life Sci . 2025 Feb; 366-367:123479. PMID: 39983828
Depression is a prevalent chronic psychiatric disorder with a growing impact on global health. Current treatments often fail to achieve full remission, highlighting the need for alternative therapeutic strategies. Mesenchymal...
2.
Nonaka C, Costa-Ferro Z, Arraes A, Weber T, de Aragao Franca L, Silva K, et al.
Hematol Transfus Cell Ther . 2025 Jan; 47(1):103727. PMID: 39863436
Mesenchymal stromal cells are multipotent cells present in various tissues that are widely studied for relevant therapeutic potential due to their paracrine immunomodulatory and tissue regenerating properties. Many mesenchymal stromal...
3.
da Silva K, Marim F, Rocha G, Costa-Ferro Z, de Aragao Franca L, Nonaka C, et al.
Stem Cell Res Ther . 2025 Jan; 16(1):15. PMID: 39849557
Background: Despite many years of investigation into mesenchymal stem cells (MSCs) and their potential for treating inflammatory conditions such as COVID-19, clinical outcomes remain variable due to factors like donor...
4.
da Silva K, Lima I, Dos Santos C, Nonaka C, Souza B, David J, et al.
Molecules . 2025 Jan; 30(1. PMID: 39795214
Glioblastomas (GBM) are malignant tumours with poor prognosis. Treatment involves chemotherapy and/or radiotherapy; however, there is currently no standard treatment for recurrence, and prognosis remains unfavourable. Inflammatory mediators and microRNAs...
5.
Macedo C, Souza B, Villarreal C, Silva D, da Silva K, de Souza C, et al.
Front Med (Lausanne) . 2024 Sep; 11:1451297. PMID: 39328312
Objective: Spinal cord injury (SCI) is a serious condition that can lead to partial or complete paraplegia or tetraplegia. Currently, there are few therapeutic options for these conditions, which are...
6.
George C, Sahu S, de Onate L, Souza B, Wilson R
CRISPR J . 2024 Sep; 7(5):231-248. PMID: 39324895
Hematopoietic stem cells (HSCs) provide the body with a continuous supply of healthy, functional blood cells. In patients with hematopoietic malignancies, immunodeficiencies, lysosomal storage disorders, and hemoglobinopathies, therapeutic genome editing...
7.
Pinheiro A, Torrecilhas A, Souza B, Cruz F, de Matos Guedes H, Ramos T, et al.
J Extracell Vesicles . 2024 Aug; 13(8):e12496. PMID: 39113589
Parasitic diseases have a significant impact on human and animal health, representing a major hazard to the public and causing economic and health damage worldwide. Extracellular vesicles (EVs) have long...
8.
Cavalcante B, Freitas R, Siquara da Rocha L, Santos R, Souza B, Ramos P, et al.
Front Pharmacol . 2024 Jun; 15:1400029. PMID: 38919258
Cancer refers to a group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. Due to its complexity, it has been hard to find...
9.
de Araujo T, Nogueira R, Siquara da Rocha L, Bastos I, Dias R, Souza B, et al.
SLAS Discov . 2024 Jun; 29(4):100158. PMID: 38852983
3D in vitro systems offer advantages over the shortcomings of two-dimensional models by simulating the morphological and functional features of in vivo-like environments, such as cell-cell and cell-extracellular matrix interactions,...
10.
Costa-Ferro Z, Rocha G, da Silva K, Paredes B, Loiola E, Silva J, et al.
Cytotherapy . 2024 May; 26(9):1013-1025. PMID: 38762805
Background Aims: Extracellular vesicles (EVs) represent a new axis of intercellular communication that can be harnessed for therapeutic purposes, as cell-free therapies. The clinical application of mesenchymal stromal cell (MSC)-derived...