Bruna Pasqualotto Costa
Overview
Explore the profile of Bruna Pasqualotto Costa including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
49
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0
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Recent Articles
1.
Reghelin C, Bastos M, de Souza Basso B, Costa B, Cruz de Sousa A, Martha B, et al.
Food Chem Toxicol
. 2025 Mar;
200:115351.
PMID: 40024562
Bezafibrate (BZF) is a drug that reduces cholesterol and triglyceride levels in the blood. Research indicates that BZF, through activation of PPAR receptors, regulates the expression of genes involved in...
2.
Catarina A, Branchini G, Caceres R, Fernandes R, Costa B, Machado K, et al.
Physiol Rep
. 2024 Oct;
12(19):e70033.
PMID: 39396923
Hypotension is one of the main characteristics of the systemic inflammation, basically caused by endothelial dysfunction. Studies have shown that the amino acid L-kynurenine (KYN) causes vasodilation in mammals, leading...
3.
Reghelin C, Bastos M, de Souza Basso B, Costa B, Lima K, Cruz de Sousa A, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2023 Jun;
396(12):3857-3866.
PMID: 37358795
In pulmonary fibrosis, the proliferation of fibroblasts and their differentiation into myofibroblasts is often caused by tissue damage, such as oxidative damage caused by reactive oxygen species, which leads to...
4.
Bastos M, Saalfeld R, Costa B, Antunes K, Melo D, Fagundes Donadio M, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2023 Jan;
396(5):1075.
PMID: 36710279
No abstract available.
5.
Bastos M, Saalfeld R, Costa B, Garcia M, Antunes K, Rodrigues K, et al.
J Ethnopharmacol
. 2022 Dec;
303:116056.
PMID: 36535332
Ethnopharmacological Relevance: The chosen plant and its extracts have been an alternative in the treatment of several inflammatory and oxidant diseases, and is therefore a viable option for the treatment...
6.
Bastos M, Saalfeld R, Costa B, Antunes K, Melo D, Fagundes Donadio M, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2022 Dec;
396(5):925-937.
PMID: 36520165
Coumaric acid is a phenolic compound found in medicinal plants. Its use has been reported in the treatment of inflammatory diseases, prevention of alterations induced by oxidative stress, as well...
7.
Costa B, Nunes F, Noal F, Branchini G
Cancers (Basel)
. 2022 Oct;
14(19).
PMID: 36230654
Uterine or endometrial cancer (EC) is the sixth most common neoplasia among women worldwide. Cancer can originate from a myriad of causes, and increasing evidence suggests that ion channels (IC)...
8.
Antunes G, Matzenbacher L, Costa B, de Sousa Basso B, Schneider Levorse V, Antunes K, et al.
Inflammation
. 2022 Mar;
45(4):1534-1547.
PMID: 35267122
Acute lung injury (ALI) is a life-threatening acute inflammatory disease with high rates of morbidity and mortality worldwide. 4-Allyl-2,6-dimethoxyphenol (methoxyeugenol), a phenylpropanoid from a synthetic source, exhibits strong anti-inflammatory activity,...
9.
Costa B, Nassr M, Diz F, Antunes Fernandes K, Antunes G, Grun L, et al.
J Ethnopharmacol
. 2020 Dec;
267:113645.
PMID: 33271245
Ethnopharmacological Relevance: Plant-derived compounds are a reservoir of natural chemicals and can act as drug precursors or prototypes and pharmacological probes. Methoxyeugenol is a natural compound found in plant extracts,...
10.
Goncalves da Silva E, Costa B, Nassr M, de Souza Basso B, Bastos M, Antunes G, et al.
Eur J Pharmacol
. 2020 Oct;
890:173670.
PMID: 33098831
Potassium 5-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-olate (CPBMF65) is a potent inhibitor of the uridine phosphorylase 1 (UPP1) enzyme. Its non-ionized analog has already demonstrated biological properties by reducing adverse effects caused by the chemotherapeutic...