Bruce A Bunnell
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Explore the profile of Bruce A Bunnell including associated specialties, affiliations and a list of published articles.
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200
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6792
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Recent Articles
11.
Al-Ghadban S, Isern S, Herbst K, Bunnell B
Biomedicines
. 2024 May;
12(5).
PMID: 38791004
Lipedema is a chronic, idiopathic, and painful disease characterized by an excess of adipose tissue in the extremities. The goal of this study is to characterize the gene expression of...
12.
Lu Y, Tian H, Peng H, Wang Q, Bunnell B, Bazan N, et al.
Front Cell Dev Biol
. 2024 Mar;
12:1380059.
PMID: 38533089
Stem cells can be used to treat diabetic mellitus and complications. ω3-docosahexaenoic acid (DHA) derived lipid mediators are inflammation-resolving and protective. This study found novel DHA-derived 7,14-dihydroxy-4,8,10,12,16,19-docosahexaenoic acid (7,14-diHDHA), a...
13.
Rinderle C, Bunnell B
Methods Mol Biol
. 2024 Mar;
2783:303-308.
PMID: 38478242
Breast cancer is an ongoing issue due to its high mortality rates. Obesity enhances the problems associated with breast cancer, meaning there must be a biological connection between them. This...
14.
Lipa K, Makarcyzk M, Hines S, Lintz C, Bunnell B, Lin H
Methods Mol Biol
. 2024 Mar;
2783:287-300.
PMID: 38478241
Adipose tissue is a complex and multifaceted endocrine organ located throughout the body. The dysfunction of adipose tissue is known to induce a wide variety of comorbidities that can negatively...
15.
Al-Ghadban S, Bunnell B
Methods Mol Biol
. 2024 Mar;
2783:263-268.
PMID: 38478238
Compared to two-dimensional monolayer culture, cells cultured in three-dimensional (3D) platforms provide a more biochemically and physiologically relevant environment to study cell-cell and cell-extracellular matrix interactions in vitro. Using the...
16.
Montano E, Al-Ghadban S, Bunnell B
Methods Mol Biol
. 2024 Mar;
2783:3-11.
PMID: 38478222
Human adipose-derived stromal/stem cells (hASCs) are a promising source of adult stem cells used in numerous applications in regenerative medicine. We present the protocols from our laboratory for isolating and...
17.
Sabnis N, Raut S, Nagarajan B, Kapic A, Serena Dossou A, Lothstein L, et al.
Bioconjug Chem
. 2024 Feb;
35(2):187-202.
PMID: 38318778
To meet the current need for a tumor-selective, targeted therapy regimen associated with reduced toxicity, our laboratory has developed a nanostructure that resembles high-density lipoproteins (HDLs). These myristoyl-5A (MYR-5A) nanotransporters...
18.
Lagarde C, Kavalakatt J, Benz M, Hawes M, Arbogast C, Cullen N, et al.
Oncogene
. 2024 Feb;
43(11):763-775.
PMID: 38310162
Both breast cancer and obesity can regulate epigenetic changes or be regulated by epigenetic changes. Due to the well-established link between obesity and an increased risk of developing breast cancer,...
19.
Al-Ghadban S, Walczak S, Isern S, Martin E, Herbst K, Bunnell B
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686378
Lipedema is a connective tissue disorder characterized by increased dilated blood vessels (angiogenesis), inflammation, and fibrosis of the subcutaneous adipose tissue. This project aims to gain insights into the angiogenic...
20.
Casy W, Garza I, Chen X, Dong T, Hu Y, Kanchwala M, et al.
Genes (Basel)
. 2023 Aug;
14(8).
PMID: 37628711
The use of AAV capsid libraries coupled with various selection strategies has proven to be a remarkable approach for generating novel AAVs with enhanced and desired features. The inability to...