Bruce A Armitage
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Explore the profile of Bruce A Armitage including associated specialties, affiliations and a list of published articles.
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71
Citations
1011
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Recent Articles
1.
Sarkar S, Colon-Roura G, Pearse A, Armitage B
Biopolymers
. 2022 Dec;
114(1):e23529.
PMID: 36573547
Growing interest in i-motif DNA as a transcriptional regulatory element motivates development of synthetic molecules capable of targeting these structures. In this study, we designed unmodified peptide nucleic acid (PNA)...
2.
3.
Goldman J, Kim S, Narburgh S, Armitage B, Schneider J
Biopolymers
. 2021 Oct;
113(2):e23479.
PMID: 34643943
miRNA is a promising class of biomarkers whose levels can be assayed to detect various forms of cancer and other serious diseases. These short, noncoding nucleic acids are difficult to...
4.
Sarkar S, Armitage B
ACS Infect Dis
. 2021 Apr;
7(6):1445-1456.
PMID: 33886274
In the United States, West Nile virus (WNV) infects approximately 2500 people per year, of which 100-200 cases are fatal. No antiviral drug or vaccine is currently available for WNV....
5.
Berlyoung A, Armitage B
Biochemistry
. 2020 Oct;
59(42):4072-4080.
PMID: 33048532
Transient association of guanine-rich RNA and DNA in the form of hetero-G-quadruplexes (RDQs) has emerged as an important mechanism for regulating genome transcription and replication but relatively little is known...
6.
Canady T, Berlyoung A, Martinez J, Emanuelson C, Telmer C, Bruchez M, et al.
Molecules
. 2020 Feb;
25(4).
PMID: 32098111
High affinity nucleic acid analogues such as gammaPNA (γPNA) are capable of invading stable secondary and tertiary structures in DNA and RNA targets but are susceptible to off-target binding to...
7.
Armitage B
Methods Mol Biol
. 2019 Aug;
2035:333-345.
PMID: 31444760
The growing interest in G-quadruplex (G4) structure and function is motivating intense efforts to develop G4-binding ligands. This chapter describes the design and testing of peptide nucleic acid (PNA) oligomers,...
8.
Tan X, Bruchez M, Armitage B
Chembiochem
. 2018 Nov;
20(5):727-733.
PMID: 30452106
Intracellular delivery and endosomal release of antisense oligonucleotides remain a significant challenge in the development of gene-targeted therapeutics. Previously, noncovalently cyclized TAT peptide (Cyc-TAT), in which the final ring-closing step...
9.
Shelke S, Shao Y, Laski A, Koirala D, Weissman B, Fuller J, et al.
Nat Commun
. 2018 Nov;
9(1):4542.
PMID: 30382099
The DIR2s RNA aptamer, a second-generation, in-vitro selected binder to dimethylindole red (DIR), activates the fluorescence of cyanine dyes, DIR and oxazole thiazole blue (OTB), allowing detection of two well-resolved...
10.
Stensrud K, Zanotti K, Waggoner A, Armitage B
Photochem Photobiol
. 2018 Oct;
95(1):406-410.
PMID: 30339278
Spectral properties and fluorogenic behaviors of five novel thiophene variants of malachite green (MG), termed MGTs, were determined. Appreciable changes as a function of homologation and substitution pattern, including absorption...