Bronislaw Pytowski
Overview
Explore the profile of Bronislaw Pytowski including associated specialties, affiliations and a list of published articles.
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45
Citations
3200
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Recent Articles
1.
Persaud K, Tille J, Liu M, Zhu Z, Jimenez X, Pereira D, et al.
J Cell Sci
. 2023 Sep;
136(17).
PMID: 37675777
No abstract available.
2.
Uhlik M, Pointing D, Iyer S, Ausec L, Stajdohar M, Cvitkovic R, et al.
Front Oncol
. 2023 May;
13:1158345.
PMID: 37251949
Introduction: Most predictive biomarkers approved for clinical use measure single analytes such as genetic alteration or protein overexpression. We developed and validated a novel biomarker with the aim of achieving...
3.
Li Y, Amaladas N, OMahony M, Manro J, Inigo I, Li Q, et al.
PLoS One
. 2022 Jul;
17(7):e0268244.
PMID: 35849586
Prolonged activation of vascular endothelial growth factor receptor-2 (VEGFR-2) due to mis-regulation of the VEGF pathway induces aberrant blood vessel expansion, which supports growth and survival of solid tumors. Therapeutic...
4.
Lowery C, Blosser W, Dowless M, Renschler M, Perez L, Stephens J, et al.
Oncotarget
. 2019 Oct;
10(53):5523-5533.
PMID: 31565186
Vascular endothelial growth factor receptor 2 (VEGFR2) is an attractive therapeutic target in solid malignancies due to its central role in tumor angiogenesis. Ramucirumab (Cyramza, LY3009806) is a human monoclonal...
5.
Das V, Kc R, Li X, O-Sullivan I, van Wijnen A, Kroin J, et al.
Gene Rep
. 2019 Mar;
11:94-100.
PMID: 30873504
Osteoarthritis (OA) is a painful and debilitating disease. A striking feature of OA is the dramatic increase in vascular endothelial growth factor (VEGF) levels and in new blood vessel formation...
6.
Hominick D, Silva A, Khurana N, Liu Y, Dechow P, Feng J, et al.
Elife
. 2018 Apr;
7.
PMID: 29620526
Patients with Gorham-Stout disease (GSD) have lymphatic vessels in their bones and their bones gradually disappear. Here, we report that mice that overexpress VEGF-C in bone exhibit a phenotype that...
7.
Saif M, Knost J, Chiorean E, Kambhampati S, Yu D, Pytowski B, et al.
Cancer Chemother Pharmacol
. 2016 Aug;
78(4):815-24.
PMID: 27566701
Purpose: Metastasis of solid tumors to regional lymph nodes is facilitated by tumor lymphangiogenesis, which is primarily mediated by the vascular endothelial growth factor receptor 3 (VEGFR-3). We conducted a...
8.
Falcon B, Chintharlapalli S, Uhlik M, Pytowski B
Pharmacol Ther
. 2016 Jun;
164:204-25.
PMID: 27288725
Interaction of numerous signaling pathways in endothelial and mesangial cells results in exquisite control of the process of physiological angiogenesis, with a central role played by vascular endothelial growth factor...
9.
Uhlik M, Liu J, Falcon B, Iyer S, Stewart J, Celikkaya H, et al.
Cancer Res
. 2016 May;
76(9):2573-86.
PMID: 27197264
Treatment of metastatic gastric cancer typically involves chemotherapy and monoclonal antibodies targeting HER2 (ERBB2) and VEGFR2 (KDR). However, reliable methods to identify patients who would benefit most from a combination...
10.
Yao L, Testini C, Tvorogov D, Anisimov A, Vargas S, Baluk P, et al.
Circ Res
. 2014 Jan;
114(5):806-22.
PMID: 24429550
Rationale: Lymphatic vessels in the respiratory tract normally mature into a functional network during the neonatal period, but under some pathological conditions they can grow as enlarged, dilated sacs that...