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Brittany K Matlock

Explore the profile of Brittany K Matlock including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 545
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Recent Articles
1.
Taylor S, McWhirter R, Matlock B, Flaherty D, Miller 3rd D
STAR Protoc . 2024 Nov; 5(4):103439. PMID: 39514392
The C. elegans nervous system is compact and well described, ideal for identifying genetic programs that drive neuron-specific development, function, and connectivity. Here, we present a protocol for isolating specific...
2.
Natri H, Del Azodi C, Peter L, Taylor C, Chugh S, Kendle R, et al.
Nat Genet . 2024 Apr; 56(5):1034. PMID: 38664563
No abstract available.
3.
Natri H, Del Azodi C, Peter L, Taylor C, Chugh S, Kendle R, et al.
Nat Genet . 2024 Mar; 56(4):595-604. PMID: 38548990
Common genetic variants confer substantial risk for chronic lung diseases, including pulmonary fibrosis. Defining the genetic control of gene expression in a cell-type-specific and context-dependent manner is critical for understanding...
4.
Natri H, Del Azodi C, Peter L, Taylor C, Chugh S, Kendle R, et al.
bioRxiv . 2023 Mar; PMID: 36993211
Common genetic variants confer substantial risk for chronic lung diseases, including pulmonary fibrosis (PF). Defining the genetic control of gene expression in a cell-type-specific and context-dependent manner is critical for...
5.
Pham L, Komalavilas P, Eddie A, Thayer T, Greenwood D, Liu K, et al.
Commun Biol . 2022 Dec; 5(1):1366. PMID: 36513703
Cellular metabolism influences immune cell function, with mitochondrial fatty acid β-oxidation and oxidative phosphorylation required for multiple immune cell phenotypes. Carnitine palmitoyltransferase 1a (Cpt1a) is considered the rate-limiting enzyme for...
6.
Florian A, Woodley C, Wang J, Grieb B, Slota M, Guerrazzi K, et al.
NAR Cancer . 2022 Mar; 4(1):zcac007. PMID: 35252869
Rhabdoid tumors (RT) are rare and deadly pediatric cancers driven by loss of , which encodes the SNF5 component of the SWI/SNF chromatin remodeler. Loss of is associated with a...
7.
Siladi A, Wang J, Florian A, Thomas L, Creighton J, Matlock B, et al.
Sci Rep . 2022 Feb; 12(1):1848. PMID: 35115608
WDR5 nucleates the assembly of histone-modifying complexes and acts outside this context in a range of chromatin-centric processes. WDR5 is also a prominent target for pharmacological inhibition in cancer. Small-molecule...
8.
Negretti N, Plosa E, Benjamin J, Schuler B, Habermann A, Jetter C, et al.
Development . 2021 Dec; 148(24). PMID: 34927678
Lung organogenesis requires precise timing and coordination to effect spatial organization and function of the parenchymal cells. To provide a systematic broad-based view of the mechanisms governing the dynamic alterations...
9.
Woodley C, Romer A, Wang J, Guarnaccia A, Elion D, Maxwell J, et al.
Oncogene . 2021 May; 40(20):3593-3609. PMID: 33931740
The SNF5 subunit of the SWI/SNF chromatin remodeling complex has been shown to act as a tumor suppressor through multiple mechanisms, including impairing the ability of the oncoprotein transcription factor...
10.
May-Zhang A, Tycksen E, Southard-Smith A, Deal K, Benthal J, Buehler D, et al.
Gastroenterology . 2020 Oct; 160(3):755-770.e26. PMID: 33010250
Background & Aims: The enteric nervous system (ENS) coordinates essential intestinal functions through the concerted action of diverse enteric neurons (ENs). However, integrated molecular knowledge of EN subtypes is lacking....