Brinda Chandar
Overview
Explore the profile of Brinda Chandar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
63
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hu Z, Leus I, Chandar B, Sherborne B, Avila Q, Rybenkov V, et al.
J Med Chem
. 2023 Sep;
66(19):13858.
PMID: 37733930
No abstract available.
2.
Leus I, Adamiak J, Chandar B, Bonifay V, Zhao S, Walker S, et al.
Antimicrob Agents Chemother
. 2023 Jan;
67(2):e0137722.
PMID: 36715507
Gram-negative bacteria are notoriously more resistant to antibiotics than Gram-positive bacteria, primarily due to the presence of the outer membrane and a plethora of active efflux pumps. However, the potency...
3.
Hu Z, Leus I, Chandar B, Sherborne B, Avila Q, Rybenkov V, et al.
J Med Chem
. 2022 Oct;
65(20):14144-14179.
PMID: 36257060
The clinical success of linezolid for treating Gram-positive infections paired with the high conservation of bacterial ribosomes predicts that if oxazolidinones were engineered to accumulate in Gram-negative bacteria, then this...
4.
Zgurskaya H, Malloci G, Chandar B, Vargiu A, Ruggerone P
Curr Opin Microbiol
. 2021 May;
61:115-123.
PMID: 33940284
All mechanisms of clinical antibiotic resistance benefit from activities of polyspecific efflux pumps acting to reduce intracellular accumulation of toxins and antibiotics. In Gram-negative bacteria, the major polyspecific efflux transporters...
5.
Chandar B, Bhattacharya D
Curr Top Med Chem
. 2019 Apr;
19(10):874-885.
PMID: 30987566
A rapid growth in drug resistance has brought options for treating antimicrobial resistance to a halt. Bacteria have evolved to accumulate a multitude of genes that encode resistance for a...
6.
Kumar R, Chandar B, Parani M
Indian J Med Res
. 2018 May;
147(1):97-101.
PMID: 29749367
Background & Objectives: New Delhi metallo-β-lactamase 1 (NDM-1) cleaves the beta-lactam ring, and confers bacterial resistance against most of the beta-lactam antibiotics, except tigecycline and colistin. Among these two antibiotics,...
7.
Chandar B, Poovitha S, Ilango K, Mohankumar R, Parani M
Front Microbiol
. 2017 Sep;
8:1580.
PMID: 28878746
Improper use of antibiotics has led to a great concern in the development of pathogenic microbial resistance. New Delhi metallo-β-lactamase 1 (NDM-1) producing bacteria are resistant to most of the...