Brigitte Simons
Overview
Explore the profile of Brigitte Simons including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
412
Followers
0
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Recent Articles
1.
Xu H, Boucher F, Nguyen T, Taylor G, Tomlinson J, Ortega R, et al.
J Lipid Res
. 2018 Nov;
60(1):200-211.
PMID: 30413651
Cerebrosides, including glucosylceramides (GlcCers) and galactosylceramides (GalCers), are important membrane components of animal cells with deficiencies resulting in devastating lysosomal storage disorders. Their quantification is essential for disease diagnosis and...
2.
Attane C, Peyot M, Lussier R, Poursharifi P, Zhao S, Zhang D, et al.
Diabetologia
. 2016 Sep;
59(12):2654-2663.
PMID: 27677764
Aims/hypothesis: To directly assess the role of beta cell lipolysis in insulin secretion and whole-body energy homeostasis, inducible beta cell-specific adipose triglyceride lipase (ATGL)-deficient (B-Atgl-KO) mice were studied under normal...
3.
Liaw L, Prudovsky I, Koza R, Anunciado-Koza R, Siviski M, Lindner V, et al.
J Cell Biochem
. 2016 Feb;
117(9):2182-93.
PMID: 26910604
Our objective was to characterize lipid profiles in cell models of adipocyte differentiation in comparison to mouse adipose tissues in vivo. A novel lipid extraction strategy was combined with global...
4.
Wilson L, Arabshahi A, Simons B, Prasain J, Barnes S
Arch Biochem Biophys
. 2014 Jun;
559:3-11.
PMID: 24967696
This study was conducted to assess the value of a high resolution, high mass accuracy time-of-flight analyzer in combination with nanoliquid chromatography for the analysis of polyphenols and their metabolites....
5.
Simons B, Kauhanen D, Sylvanne T, Tarasov K, Duchoslav E, Ekroos K
Metabolites
. 2014 Jun;
2(1):195-213.
PMID: 24957374
Shotgun lipidomics has evolved into a myriad of multi-dimensional strategies for molecular lipid characterization, including bioinformatics tools for mass spectrum interpretation and quantitative measurements to study systems-lipidomics in complex biological...
6.
Li Q, Zhang S, Berthiaume J, Simons B, Zhang G
J Lipid Res
. 2013 Dec;
55(3):592-602.
PMID: 24367045
A metabolomic approach to selectively profile all acyl-CoAs was developed using a programmed multiple reaction monitoring (MRM) method in LC-MS/MS and was employed in the analysis of various rat organs....
7.
Arendt B, Ma D, Simons B, Noureldin S, Therapondos G, Guindi M, et al.
Appl Physiol Nutr Metab
. 2013 Mar;
38(3):334-40.
PMID: 23537027
Nonalcoholic fatty liver disease (NAFLD) is associated with altered hepatic lipid composition. Animal studies suggest that the hepatic ratio of phosphatidylcholine (PC) to phosphatidylethanolamine (PE) contributes to steatogenesis and inflammation....
8.
Zhu M, Dai S, Zhu N, Booy A, Simons B, Yi S, et al.
J Proteome Res
. 2012 May;
11(7):3728-42.
PMID: 22639841
Stomata on leaf epidermis formed by pairs of guard cells control CO(2) intake and water transpiration, and respond to different environmental conditions. Stress-induced stomatal closure is mediated via an intricate...
9.
Cheema A, Knights C, Rao M, Catania J, Perez R, Simons B, et al.
J Cell Physiol
. 2010 May;
225(2):371-84.
PMID: 20458745
The ubiquitin-like molecule, SUMO-1, a small protein essential for a variety of biological processes, is covalently conjugated to many intracellular proteins, especially to regulatory components of the transcriptional machinery, such...
10.
Zhu M, Simons B, Zhu N, Oppenheimer D, Chen S
J Proteomics
. 2009 Nov;
73(4):790-805.
PMID: 19913118
Guard cells, which form stomata on the leaf epidermis, play important roles in plant gas exchange and defense against pathogens. Abscisic acid (ABA) is a phytohormone that can be induced...