Brigitte Crouau-Roy
Overview
Explore the profile of Brigitte Crouau-Roy including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
409
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Recent Articles
1.
Boukouvala S, Drakomathioulaki N, Papanikolaou G, Tsirka T, Veyssiere C, Sabbagh A, et al.
Biochem Pharmacol
. 2021 Apr;
188:114545.
PMID: 33831395
Human NAT2 is a polymorphic pharmacogene encoding for N-acetyltransferase 2, a hepatic enzyme active towards arylamine and arylhydrazine drugs, including the anti-tubercular antibiotic isoniazid. The isoenzyme also modulates susceptibility to...
2.
Shearn R, Wright A, Mousset S, Regis C, Penel S, Lemaitre J, et al.
Elife
. 2020 Nov;
9.
PMID: 33205751
Sex chromosomes are typically comprised of a non-recombining region and a recombining pseudoautosomal region. Accurately quantifying the relative size of these regions is critical for sex-chromosome biology both from a...
3.
Boukouvala S, Chasapopoulou Z, Giannouri D, Kontomina E, Marinakis N, Rizou S, et al.
Sci Rep
. 2019 Jul;
9(1):10937.
PMID: 31358821
Human NAT1 gene for N-acetyltransferase 1 modulates xenobiotic metabolism of arylamine drugs and mutagens. Beyond pharmacogenetics, NAT1 is also relevant to breast cancer. The population history of human NAT1 suggests...
4.
Vangenot C, Gagneux P, de Groot N, Baumeyer A, Mouterde M, Crouau-Roy B, et al.
G3 (Bethesda)
. 2019 May;
9(7):2199-2224.
PMID: 31068377
Among the many genes involved in the metabolism of therapeutic drugs, human arylamine -acetyltransferases () genes have been extensively studied, due to their medical importance both in pharmacogenetics and disease...
5.
Tsirka T, Konstantopoulou M, Sabbagh A, Crouau-Roy B, Ryan A, Sim E, et al.
Sci Rep
. 2018 Jun;
8(1):9759.
PMID: 29950659
Xenobiotic metabolising N-acetyltransferases (NATs) perform biotransformation of drugs and carcinogens. Human NAT1 is associated with endogenous metabolic pathways of cells and is a candidate drug target for cancer. Human NAT2...
6.
Lecompte E, Bouanani M, De Thoisy B, Crouau-Roy B
Am J Primatol
. 2017 Mar;
79(7).
PMID: 28346698
Dispersal, one of the major factors affecting the gene flow between populations, shapes the spatial distribution of genetic diversity within species. Alouatta macconnelli and Saguinus midas are two Neotropical monkey...
7.
Salmier A, De Thoisy B, Crouau-Roy B, Lacoste V, Lavergne A
BMC Evol Biol
. 2016 Oct;
16(1):229.
PMID: 27782798
Background: Although bats are natural reservoirs of many pathogens, few studies have been conducted on the genetic variation and detection of selection in major histocompatibility complex (MHC) genes. These genes...
8.
Lecompte E, Bouanani M, Magro A, Crouau-Roy B
Ecol Evol
. 2016 Aug;
6(15):5517-29.
PMID: 27551401
Population genetics and phenotypic structures are often predicted to vary along the geographic range of a species. This phenomenon would be accentuated for species with large range areas, with discontinuities...
9.
Complete mitochondrial genome of the gray mouse lemur, Microcebus murinus (Primates, Cheirogaleidae)
Lecompte E, Crouau-Roy B, Aujard F, Holota H, Murienne J
Mitochondrial DNA A DNA Mapp Seq Anal
. 2016 May;
27(5):3514-6.
PMID: 27158869
We report the high-coverage complete mitochondrial genome sequence of the gray mouse lemur Microcebus murinus. The sequencing has been performed on an Illumina Hiseq 2500 platform, with a genome skimming...
10.
Quemere E, Hibert F, Miquel C, Lhuillier E, Rasolondraibe E, Champeau J, et al.
PLoS One
. 2013 Mar;
8(3):e58971.
PMID: 23527060
In tropical regions, most primary ecosystems have been replaced by mosaic landscapes in which species must cope with a large shift in the distribution of their habitat and associated food...