Nel Otting
Overview
Explore the profile of Nel Otting including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
1024
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Recent Articles
1.
Bruijnesteijn J, de Groot N, van der Wiel M, Otting N, de Vos-Rouweler A, de Groot N, et al.
J Immunol
. 2020 Mar;
204(7):1770-1786.
PMID: 32111732
The killer cell Ig-like receptors (KIR) modulate immune responses through interactions with MHC class I molecules. The region in large cohorts of rhesus and cynomolgus macaque populations were characterized, and...
2.
Kondova I, Braskamp G, Heidt P, Collignon W, Haaksma T, de Groot N, et al.
Primate Biol
. 2020 Feb;
4(1):117-125.
PMID: 32110699
Endometriosis is a poorly understood common debilitating women's reproductive disorder resulting from proliferative and ectopic endometrial tissue associated with variable clinical symptoms including dysmenorrhea (painful menstrual periods), dyspareunia (pain on...
3.
de Groot N, Heijmans C, de Ru A, Otting N, Koning F, Van Veelen P, et al.
J Virol
. 2020 Feb;
94(9).
PMID: 32075930
The major histocompatibility complex (MHC) class I region of humans, chimpanzees (), and bonobos () is highly similar, and orthologues of , -, and - are present in both species....
4.
Bruijnesteijn J, de Groot N, Otting N, Maccari G, Guethlein L, Robinson J, et al.
Immunogenetics
. 2019 Nov;
72(1-2):37-47.
PMID: 31781789
The Killer-cell Immunoglobulin-like Receptors (KIR) are encoded by a diverse group of genes, which are characterized by allelic polymorphism, gene duplications, and recombinations, which may generate recombinant entities. The number...
5.
de Groot N, Otting N, Maccari G, Robinson J, Hammond J, Blancher A, et al.
Immunogenetics
. 2019 Nov;
72(1-2):131-132.
PMID: 31745605
The original version of this article contained a spelling error in the Acknowledgments regarding the name of the funding organisation supporting GM and JAH. UKRI-BBSCR should have been UKRI-BBSRC, as...
6.
Otting N, de Groot N, Bontrop R
HLA
. 2019 Nov;
95(2):163-165.
PMID: 31705598
Thirty newly identified full-length MHC class II alleles in three New World monkey species.
7.
de Groot N, Otting N, Maccari G, Robinson J, Hammond J, Blancher A, et al.
Immunogenetics
. 2019 Oct;
72(1-2):25-36.
PMID: 31624862
The major histocompatibility complex (MHC) is central to the innate and adaptive immune responses of jawed vertebrates. Characteristic of the MHC are high gene density, gene copy number variation, and...
8.
Bruijnesteijn J, van der Wiel M, de Groot N, Otting N, de Vos-Rouweler A, Lardy N, et al.
Front Immunol
. 2018 Dec;
9:2846.
PMID: 30564240
The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules. The complexity of the cluster is reflected by, for...
9.
Otting N, de Groot N, Bontrop R
Immunogenetics
. 2018 Oct;
70(10):689-691.
PMID: 30283990
The authors regret that an error was present in the Fig. 5 of the above article; some digits in the DRB allele-designations in Fig. 5 have been lost, and are...
10.
Otting N, de Groot N, Bontrop R
Immunogenetics
. 2018 Aug;
71(1):13-23.
PMID: 30159708
Chimpanzees have been used for some time as an animal model in research on immune-related diseases in humans. The major histocompatibility complex (MHC) region of the chimpanzee has also been...