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Brian T Wilson

Explore the profile of Brian T Wilson including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 332
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Recent Articles
1.
Apelt K, White S, Kim H, Yeo J, Kragten A, Wondergem A, et al.
J Exp Med . 2020 Dec; 218(3). PMID: 33315086
ERCC1-XPF is a multifunctional endonuclease involved in nucleotide excision repair (NER), interstrand cross-link (ICL) repair, and DNA double-strand break (DSB) repair. Only two patients with bi-allelic ERCC1 mutations have been...
2.
van Dijk F, Semler O, Etich J, Kohler A, Jimenez-Estrada J, Bravenboer N, et al.
Am J Hum Genet . 2020 Oct; 107(5):989-999. PMID: 33053334
Osteogenesis imperfecta (OI) is characterized primarily by susceptibility to fractures with or without bone deformation. OI is genetically heterogeneous: over 20 genetic causes are recognized. We identified bi-allelic pathogenic KDELR2...
3.
Wilson B, Hughes J
Arch Dis Child . 2019 Jun; 105(2):107-108. PMID: 31196911
No abstract available.
4.
Meyer E, Carss K, Rankin J, Nichols J, Grozeva D, Joseph A, et al.
Nat Genet . 2017 May; 49(6):969. PMID: 28546572
No abstract available.
5.
McCormick A, Earp E, Elliot K, Cuthbert G, ODonnell R, Wilson B, et al.
Oncotarget . 2017 May; 8(16):26832-26844. PMID: 28460465
Background: Cell lines provide a powerful model to study cancer and here we describe a new spontaneously immortalised epithelial ovarian cancer cell line (NUOC-1) derived from the ascites collected at...
6.
Meyer E, Carss K, Rankin J, Nichols J, Grozeva D, Joseph A, et al.
Nat Genet . 2016 Dec; 49(2):223-237. PMID: 27992417
Histone lysine methylation, mediated by mixed-lineage leukemia (MLL) proteins, is now known to be critical in the regulation of gene expression, genomic stability, cell cycle and nuclear architecture. Despite MLL...
7.
Munkley J, Vodak D, Livermore K, James K, Wilson B, Knight B, et al.
EBioMedicine . 2016 Jul; 8:103-116. PMID: 27428423
Steroid androgen hormones play a key role in the progression and treatment of prostate cancer, with androgen deprivation therapy being the first-line treatment used to control cancer growth. Here we...
8.
Wilson B, Lochan A, Stark Z, Sutton R
Am J Med Genet A . 2016 Jan; 170(3):773-6. PMID: 26749132
Cockayne syndrome is caused by biallelic ERCC8 (CSA) or ERCC6 (CSB) mutations and is characterized by growth restriction, microcephaly, developmental delay, and premature pathological aging. Typically affected patients also have...
9.
Munkley J, Oltean S, Vodak D, Wilson B, Livermore K, Zhou Y, et al.
Oncotarget . 2015 Oct; 6(33):34358-74. PMID: 26452038
Patterns of glycosylation are important in cancer, but the molecular mechanisms that drive changes are often poorly understood. The androgen receptor drives prostate cancer (PCa) development and progression to lethal...
10.