Brian S Bowser
Overview
Explore the profile of Brian S Bowser including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
171
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Recent Articles
1.
Alam S, Bowser B, Israr M, Conway M, Meyers C
Cancer Biol Ther
. 2014 May;
15(8):1013-28.
PMID: 24834917
We have previously reported that infection with the non-pathogenic, tumor suppressive, wild-type adeno-associated virus type 2 (AAV2) inhibited proliferation of breast cancer-derived lines representing both weakly invasive (MCF-7 and MDA-MB-468),...
2.
Alam S, Bowser B, Conway M, Israr M, Tandon A, Meyers C
Mol Cancer
. 2011 Aug;
10:97.
PMID: 21827643
Background: In normal cells proliferation and apoptosis are tightly regulated, whereas in tumor cells the balance is shifted in favor of increased proliferation and reduced apoptosis. Anticancer agents mediate tumor...
3.
Bowser B, Chen H, Conway M, Christensen N, Meyers C
Virus Res
. 2011 Jul;
160(1-2):246-55.
PMID: 21762735
Papillomaviruses (PVs) comprise a large family of viruses infecting nearly all vertebrate species, with more than 100 human PVs identified. Our previous studies showed that a mutant chimera HPV18/16 genome,...
4.
Bowser B, Alam S, Meyers C
J Virol
. 2011 Mar;
85(10):4982-92.
PMID: 21367897
Numerous epidemiological studies have implicated cigarette smoking as a cofactor in the progression to cervical cancer. Tobacco-associated hydrocarbons have been found in cervical mucus, suggesting a possible interaction with human...
5.
Alam S, Bowser B, Conway M, Israr M, Ryndock E, Xi L, et al.
J Virol
. 2010 Feb;
84(9):4630-45.
PMID: 20181698
Epidemiological studies suggest that human papillomavirus (HPV)-infected women who smoke face an increased risk for developing cervical cancer. We have previously reported that exposure of HPV-positive organotypic cultures to benzo[a]pyrene...
6.
Bowser B, Morris S, Song M, Sun R, Damania B
Virology
. 2006 Mar;
348(2):309-27.
PMID: 16546233
The K1 gene of Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a 46-kDa transmembrane glycoprotein that possesses transforming properties, initiates signaling pathways in B cells, and prevents apoptosis. Here, we demonstrate a...
7.
Gonzalez C, Wong E, Bowser B, Hong G, Kenney S, Damania B
J Virol
. 2006 Feb;
80(6):3062-70.
PMID: 16501115
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Kaposi's sarcoma is the most common neoplasm among human immunodeficiency virus-positive individuals....
8.
Damania B, Jeong J, Bowser B, DeWire S, Staudt M, Dittmer D
J Virol
. 2004 Apr;
78(10):5491-9.
PMID: 15113928
The viral immediate-early transactivator Rta/Orf50 is necessary and sufficient to initiate Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) reactivation from latently infected cells. Since Rta/Orf50 is conserved among all known gamma-2-herpesviruses,...
9.
Bowser B, DeWire S, Damania B
J Virol
. 2002 Nov;
76(24):12574-83.
PMID: 12438583
The K1 protein of Kaposi's sarcoma-associated herpesvirus (KSHV) has been shown to be a transforming protein capable of inducing morphological changes and focus formation in rodent fibroblasts. K1 can activate...