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Brian R Mosier

Explore the profile of Brian R Mosier including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Mosier B, Bantis L
Stat Methods Med Res . 2024 Mar; 33(4):647-668. PMID: 38445348
The performance of individual biomarkers in discriminating between two groups, typically the healthy and the diseased, may be limited. Thus, there is interest in developing statistical methodologies for biomarker combinations...
2.
Bantis L, Young K, Tsimikas J, Mosier B, Gajewski B, Yeatts S, et al.
Res Methods Med Health Sci . 2023 Apr; 4(1):34-48. PMID: 37009524
Studies that investigate the performance of prognostic and predictive biomarkers are commonplace in medicine. Evaluating the performance of biomarkers is challenging in traumatic brain injury (TBI) and other conditions when...
3.
Mosier B, Bantis L
Stat Med . 2021 Jun; 40(20):4522-4539. PMID: 34080733
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive type of cancer with a 5-year survival rate of less than 5%. As in many other diseases, its diagnosis might involve progressive stages....
4.
Swint-Kruse L, Martin T, Page B, Wu T, Gerhart P, Dougherty L, et al.
Protein Sci . 2021 Jun; 30(9):1833-1853. PMID: 34076313
When amino acids vary during evolution, the outcome can be functionally neutral or biologically-important. We previously found that substituting a subset of nonconserved positions, "rheostat" positions, can have surprising effects...