Brian M Peters
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Explore the profile of Brian M Peters including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Martin I, Silverberg M, Abdelgawad A, Tanaka K, Halloran B, Nicola T, et al.
Microbiome
. 2025 Jan;
13(1):24.
PMID: 39871397
Background: The immature lungs of very preterm infants are exposed to supraphysiologic oxygen, contributing to bronchopulmonary dysplasia (BPD), a chronic lung disease that is the most common morbidity of prematurity....
2.
Miao J, Williams D, Kruppa M, Peters B
mSphere
. 2024 Sep;
9(10):e0057524.
PMID: 39315809
To adapt to various host microenvironments, the human fungal pathogen possesses the capacity to accumulate and store glycogen as an internal carbohydrate source. In the model yeast , Glc7p and...
3.
Lin J, Miao J, Schaefer K, Russell C, Pyron R, Zhang F, et al.
Nat Microbiol
. 2024 Sep;
9(10):2553-2569.
PMID: 39285260
Candidalysin, a cytolytic peptide produced by the fungal pathogen Candida albicans, is a key virulence factor. However, its host cell targets remain elusive. Here we performed a genome-wide loss-of-function CRISPR...
4.
Jaswal K, Todd O, Flores Audelo R, Santus W, Paul S, Singh M, et al.
bioRxiv
. 2024 Aug;
PMID: 39211098
Enteric pathogens engage in complex interactions with the host and the resident microbiota to establish gut colonization. Although mechanistic interactions between enteric pathogens and bacterial commensals have been extensively studied,...
5.
Mangrum M, Vogel A, Wagner A, King A, Miao J, Zhou Y, et al.
mSphere
. 2024 Aug;
9(9):e0028724.
PMID: 39115319
The uridine derivatives UDP-glucose and UDP--acetylglucosamine are important for cell wall construction as they are the precursors for the synthesis of β-1,3-glucan and chitin, respectively. Previous studies have demonstrated attenuated...
6.
Paul S, Todd O, Eichelberger K, Tkaczyk C, Sellman B, Noverr M, et al.
Nat Commun
. 2024 Jul;
15(1):5746.
PMID: 38982056
Candida albicans and Staphylococcus aureus are two commonly associated pathogens that cause nosocomial infections with high morbidity and mortality. Our prior and current work using a murine model of polymicrobial...
7.
Reitler P, Regan J, DeJarnette C, Srivastava A, Carnahan J, Tucker K, et al.
Infect Immun
. 2024 Jun;
92(7):e0007224.
PMID: 38899880
Invasive fungal infections impose an enormous clinical, social, and economic burden on humankind. One of the most common species responsible for invasive fungal infections is . More than 30% of...
8.
A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by
Lin J, Miao J, Schaefer K, Russell C, Pyron R, Zhang F, et al.
bioRxiv
. 2024 Jun;
PMID: 38826446
Candidalysin is a cytolytic peptide produced by the opportunistic fungal pathogen This peptide is a key virulence factor in mouse models of mucosal and hematogenously disseminated candidiasis. Despite intense interest...
9.
Reitler P, Regan J, DeJarnette C, Srivastava A, Carnahan J, Tucker K, et al.
bioRxiv
. 2024 Feb;
PMID: 38405954
Invasive fungal infections (IFIs) impose an enormous clinical, social, and economic burden on humankind. For many IFIs, ≥ 30% of patients fail therapy with existing antifungal drugs, including the widely...
10.
Paul S, Todd O, Eichelberger K, Tkaczyk C, Sellman B, Noverr M, et al.
bioRxiv
. 2024 Feb;
PMID: 38405692
and are two commonly associated pathogens that cause nosocomial infections with high morbidity and mortality. Our prior and current work using a murine model of polymicrobial intra-abdominal infection (IAI) uncovered...