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Brian J DelFraino

Explore the profile of Brian J DelFraino including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Krungkrai S, DelFraino B, Smiley J, Prapunwattana P, Mitamura T, Horii T, et al.
Biochemistry . 2005 Feb; 44(5):1643-52. PMID: 15683248
Human malaria parasite, Plasmodium falciparum, can only synthesize pyrimidine nucleotides using the de novo pathway, whereas mammalian cells obtain pyrimidine nucleotides from both the de novo and salvage pathways. The...
2.
Smiley J, DelFraino B, Simpson B
Arch Biochem Biophys . 2003 Apr; 412(2):267-71. PMID: 12667491
The mechanism of the enzyme orotidine-5(')-monophosphate decarboxylase (OMP decarboxylase, ODCase) is not fully characterized; some of the proposed mechanisms suggest the possibility of hydrogen rearrangement (shift from C5 to C6...