Brian H Johnstone
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Explore the profile of Brian H Johnstone including associated specialties, affiliations and a list of published articles.
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38
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2383
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Recent Articles
1.
Johnstone B, Gu D, Lin C, Du J, Woods E
Cryobiology
. 2023 Oct;
113:104592.
PMID: 37827209
Clinical development of cellular therapies, including mesenchymal stem/stromal cell (MSC) treatments, has been hindered by ineffective cryopreservation methods that result in substantial loss of post-thaw cell viability and function. Proposed...
2.
Forcier R, Heussner R, Newsom L, Giers M, Al Rawashdeh W, Buchanan K, et al.
Cryobiology
. 2023 Jul;
112:104558.
PMID: 37451668
The ability to cryopreserve bone marrow within the vertebral body (VB) would offer significant clinical and research benefits. However, cryopreservation of large structures, such as VBs, is challenging due to...
3.
Johnstone B, Woods J, Goebel W, Gu D, Lin C, Miller H, et al.
Transplant Cell Ther
. 2022 Nov;
29(2):95.e1-95.e10.
PMID: 36402456
Despite the readily available graft sources for allogeneic hematopoietic cell transplantation (alloHCT), a significant unmet need remains in the timely provision of suitable unrelated donor grafts. This shortage is related...
4.
Johnstone B, Messner F, Brandacher G, Woods E
Front Immunol
. 2021 Mar;
12:622604.
PMID: 33732244
Induction of immune tolerance for solid organ and vascular composite allografts is the Holy Grail for transplantation medicine. This would obviate the need for life-long immunosuppression which is associated with...
5.
Johnstone B, Miller H, Beck M, Gu D, Thirumala S, LaFontaine M, et al.
Cytotherapy
. 2020 Sep;
22(11):617-628.
PMID: 32873509
Background: Therapeutic allogeneic mesenchymal stromal cells (MSCs) are currently in clinical trials to evaluate their effectiveness in treating many different disease indications. Eventual commercialization for broad distribution will require further...
6.
Woods E, Sherry A, Woods J, Hardin J, LaFontaine M, Brandacher G, et al.
J Transl Med
. 2020 Aug;
18(1):300.
PMID: 32758261
Background: Deceased organ donors represent an untapped source of therapeutic bone marrow (BM) that can be recovered in 3-5 times the volume of that obtained from living donors, tested for...
7.
Tauber Z, Cizkova K, Janikova M, Jurcikova J, Vitkova K, Pavliska L, et al.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
. 2018 Sep;
163(2):132-140.
PMID: 30198519
Aim: The therapeutic potential of adipose-derived stem cell conditioned medium (ASC-CM) was studied in the rabbit model of critical limb ischemia (CLI). Methods: Rabbits received treatment with ASC-CM or placebo....
8.
Prochazka V, Jurcikova J, Vitkova K, Pavliska L, Porubova L, Lassak O, et al.
Med Sci Monit
. 2018 Jan;
24:511-522.
PMID: 29371587
BACKGROUND Paracrine factors secreted by adipose-derived stem cells can be captured, fractionated, and concentrated to produce therapeutic factor concentrate (TFC). The present study examined whether TFC effects could be enhanced...
9.
Bhatnagar A, Bolli R, Johnstone B, Traverse J, Henry T, Pepine C, et al.
Am Heart J
. 2016 Sep;
179:142-50.
PMID: 27595689
Background: Although several preclinical studies have shown that bone marrow cell (BMC) transplantation promotes cardiac recovery after myocardial infarction, clinical trials with unfractionated bone marrow have shown variable improvements in...
10.
Zhong Z, Gu H, Peng J, Wang W, Johnstone B, March K, et al.
Oncotarget
. 2016 May;
7(24):36829-36841.
PMID: 27167204
Adipose tissue stroma contains a population of mesenchymal stem cells (MSC) promote new blood vessel formation and stabilization. These adipose-derived stem cells (ASC) promote de novo formation of vascular structures...