Brian H Chen
Overview
Explore the profile of Brian H Chen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
54
Citations
4897
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Gladyshev V, Anderson B, Barlit H, Barre B, Beck S, Behrouz B, et al.
PNAS Nexus
. 2024 Dec;
3(12):pgae499.
PMID: 39660064
To gain insight into how researchers of aging perceive the process they study, we conducted a survey among experts in the field. While highlighting some common features of aging, the...
2.
Herzog C, Goeminne L, Poganik J, Barzilai N, Belsky D, Betts-LaCroix J, et al.
Nat Aging
. 2024 Sep;
4(10):1372-1383.
PMID: 39285015
Biomarkers of aging (BOA) are quantitative parameters that predict biological age and ideally its changes in response to interventions. In recent years, many promising molecular and omic BOA have emerged...
3.
Bartolomucci A, Kane A, Gaydosh L, Razzoli M, McCoy B, Ehninger D, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Aug;
79(9).
PMID: 39126297
For centuries, aging was considered inevitable and immutable. Geroscience provides the conceptual framework to shift this focus toward a new view that regards aging as an active biological process, and...
4.
Chen B, Zhou W
Bioinformatics
. 2024 Jul;
40(7).
PMID: 38963309
Motivation: Infinium DNA methylation BeadChips are widely used for genome-wide DNA methylation profiling at the population scale. Recent updates to probe content and naming conventions in the EPIC version 2...
5.
Moqri M, Herzog C, Poganik J, Ying K, Justice J, Belsky D, et al.
Nat Med
. 2024 Feb;
30(2):360-372.
PMID: 38355974
The search for biomarkers that quantify biological aging (particularly 'omic'-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the...
6.
Razzoli M, Nyuyki-Dufe K, Chen B, Bartolomucci A
Proc Natl Acad Sci U S A
. 2023 Apr;
120(16):e2211755120.
PMID: 37043532
Sustained life stress and low socioeconomic status are among the major causes of aging-related diseases and decreased life expectancy. Experimental rodent models can help to identify the underlying mechanisms, yet...
7.
Chen B
Front Aging
. 2022 Sep;
3:901841.
PMID: 36176975
The maturation of machine learning and technologies that generate high dimensional data have led to the growth in the number of predictive models, such as the "epigenetic clock". While powerful,...
8.
Zhou W, Hinoue T, Barnes B, Mitchell O, Iqbal W, Lee S, et al.
Cell Genom
. 2022 Jul;
2(7).
PMID: 35873672
We have developed a mouse DNA methylation array that contains 296,070 probes representing the diversity of mouse DNA methylation biology. We present a mouse methylation atlas as a rich reference...
9.
Sun E, Qian Y, Oppong R, Butler T, Zhao J, Chen B, et al.
Aging (Albany NY)
. 2021 Oct;
13(20):23471-23516.
PMID: 34718232
It is widely thought that individuals age at different rates. A method that measures "physiological age" or physiological aging rate independent of chronological age could therefore help elucidate mechanisms of...
10.
Shadyab A, McEvoy L, Horvath S, Whitsel E, Rapp S, Espeland M, et al.
J Gerontol A Biol Sci Med Sci
. 2021 Aug;
77(6):1239-1244.
PMID: 34417803
Background: Epigenetic age acceleration (AgeAccel), which indicates faster biological aging relative to chronological age, has been associated with lower cognitive function. However, the association of AgeAccel with mild cognitive impairment...