Brian D Gregory
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Explore the profile of Brian D Gregory including associated specialties, affiliations and a list of published articles.
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127
Citations
5988
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Recent Articles
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2.
Nakano Y, Gamper H, McGuigan H, Maharjan S, Li J, Sun Z, et al.
Nat Commun
. 2025 Jan;
16(1):1047.
PMID: 39865096
While all native tRNAs undergo extensive post-transcriptional modifications as a mechanism to regulate gene expression, mapping these modifications remains challenging. The critical barrier is the difficulty of readthrough of modifications...
3.
Ganguly D, Li Y, Bhat S, Tiwari S, Ng P, Gregory B, et al.
New Phytol
. 2024 Oct;
245(1):183-199.
PMID: 39462792
Among many mRNA modifications, adenine methylation at the N position (N-methyladenosine, mA) is known to affect mRNA biology extensively. The influence of mA has yet to be assessed under drought,...
4.
Palos K, Nelson Dittrich A, Lyons E, Gregory B, Nelson A
BMC Plant Biol
. 2024 Aug;
24(1):768.
PMID: 39134938
Background: In recent years, covalent modifications on RNA nucleotides have emerged as pivotal moieties influencing the structure, function, and regulatory processes of RNA Polymerase II transcripts such as mRNAs and...
5.
Wu Y, Shao W, Yan M, Wang Y, Xu P, Huang G, et al.
Nat Commun
. 2024 May;
15(1):4049.
PMID: 38744925
Nanopore direct RNA sequencing (DRS) has emerged as a powerful tool for RNA modification identification. However, concurrently detecting multiple types of modifications in a single DRS sample remains a challenge....
6.
Sharma B, Govindan G, Li Y, Sunkar R, Gregory B
Noncoding RNA
. 2024 Feb;
10(1).
PMID: 38392963
Recently, post-transcriptional regulation of mRNA mediated by N-methyladenosine (mA) has been found to have profound effects on transcriptome regulation during plant responses to various abiotic stresses. However, whether this RNA...
7.
Guo R, Gregory B
Plant Direct
. 2023 Dec;
7(12):e553.
PMID: 38149303
Various messenger RNA (mRNA) decay mechanisms play major roles in controlling mRNA quality and quantity in eukaryotic organisms under different conditions. While it is known that the recently discovered co-translational...
8.
Li C, Shin H, Bhavanasi D, Liu M, Yu X, Peslak S, et al.
bioRxiv
. 2023 Dec;
PMID: 38077058
Hematopoietic stem cell (HSC) transplantation using umbilical cord blood (UCB) is a potentially life-saving treatment for leukemia and bone marrow failure but is limited by the low number of HSCs...
9.
Baumer Z, Erber L, Jolley E, Lawrence S, Lin C, Murakami S, et al.
Trends Biochem Sci
. 2023 Oct;
49(3):185-188.
PMID: 37884411
Post-transcriptional modifications of RNA (PRMs) and post-translational modifications of proteins (PTMs) are important regulatory mechanisms in biological processes and have many commonalities. However, the integration of these research areas is...
10.
Prall W, Sheikh A, Bazin J, Bigeard J, Almeida-Trapp M, Crespi M, et al.
Plant Cell
. 2023 Aug;
35(11):4155-4172.
PMID: 37610247
Posttranscriptional regulation of mRNA mediated by methylation at the N6 position of adenine (N6-methyladenosine [m6A]) has profound effects on transcriptome regulation in plants. Focused studies across eukaryotes offer glimpses into...