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Brian C Bales

Explore the profile of Brian C Bales including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 127
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Recent Articles
1.
Heimer M, Sun Y, Grosu S, Cyran C, Bonitatibus Jr P, Okwelogu N, et al.
Eur Radiol Exp . 2024 Oct; 8(1):108. PMID: 39365418
Background: To assess thoracic vascular computed tomography (CT) contrast enhancement of a novel intravenous tantalum oxide nanoparticle contrast agent (carboxybetaine zwitterionic tantalum oxide, TaCZ) compared to a conventional iodinated contrast...
2.
Bales B, Cotero V, Meyer D, Roberts J, Rodriguez-Silva M, Siclovan T, et al.
ACS Med Chem Lett . 2022 Oct; 13(10):1606-1614. PMID: 36262398
The c-Jun N-terminal kinase 3 (JNK3) is a stress-activated kinase primarily expressed in the brain and implicated as an early mediator of neuronal apoptosis. We sought to develop a PET...
3.
Bales B, Grimmond B, Johnson B, Luttrell M, Meyer D, Polyanskaya T, et al.
Contrast Media Mol Imaging . 2020 Jan; 2019:8356931. PMID: 31969797
Contrast-enhanced magnetic resonance imaging is an essential tool for disease diagnosis and management; all marketed clinical magnetic resonance imaging (MRI) contrast agents (CAs) are gadolinium (Gd) chelates and most are...
4.
Pai A, Pai M, Meyer D, Bales B, Cotero V, Zheng N, et al.
Regul Toxicol Pharmacol . 2018 Jun; 97:17-23. PMID: 29857115
Intravenous (IV) iron formulations are complex colloidal suspensions of iron oxide nanoparticles. Small changes in formulation can allow more labile iron to be released after injection causing toxicity. Thus, bioequivalence...
5.
Dixon W, Blezek D, Lowery L, Meyer D, Kulkarni A, Bales B, et al.
Magn Reson Med . 2009 Feb; 61(5):1132-6. PMID: 19215047
Rat legs directly injected with superparamagnetic iron oxide (SPIO) were studied by dual-echo, gradient-echo imaging. The amount of iron injected was estimated using a point dipole model for the SPIO...
6.
Osako T, Watson E, Dehestani A, Bales B, Mayer J
Angew Chem Int Ed Engl . 2006 Nov; 45(44):7433-6. PMID: 17086587
No abstract available.
7.
Bales B, Kodama T, Weledji Y, Pitie M, Meunier B, Greenberg M
Nucleic Acids Res . 2005 Sep; 33(16):5371-9. PMID: 16186134
Copper-phenanthroline complexes oxidatively damage and cleave nucleic acids. Copper bis-phenanthroline and copper complexes of mono- and bis-phenanthroline conjugates are used as research tools for studying nucleic acid structure and binding...
8.
Bales B, Brown P, Dehestani A, Mayer J
J Am Chem Soc . 2005 Mar; 127(9):2832-3. PMID: 15740101
Aqueous alkaline OsO4 at 85 degrees C oxidizes saturated alkanes, including primary, secondary, and tertiary C-H bonds. Isobutane affords tert-butanol in quantitative yield based on consumed OsO4. Cyclohexane is oxidized...
9.
Greenberg M, Weledji Y, Kim J, Bales B
Biochemistry . 2004 Jun; 43(25):8178-83. PMID: 15209514
2-Deoxyribonolactone (L) and the C4'-oxidized abasic site (C4-AP) are produced by a variety of DNA-damaging agents. If not repaired, these lesions can be mutagenic. Exonuclease III and endonuclease IV are...
10.
Bales B, Pitie M, Meunier B, Greenberg M
J Am Chem Soc . 2002 Aug; 124(31):9062-3. PMID: 12149005
Copper-phenanthroline complexes and their conjugates are useful reagents for studying nucleic acid interactions. Although DNA cleavage by such complexes was discovered more than 20 years ago, significant questions remain unanswered...