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Brian B Silver

Explore the profile of Brian B Silver including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 42
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Recent Articles
1.
Perera L, Brown S, Silver B, Tokar E, Sinha B
Int J Mol Sci . 2025 Jan; 26(2). PMID: 39859349
Acquired resistance to chemotherapeutic drugs is the primary cause of treatment failure in the clinic. While multiple factors contribute to this resistance, increased expression of ABC transporters-such as P-glycoprotein (P-gp),...
2.
Sinha B, Murphy C, Brown S, Silver B, Tokar E, Bortner C
Int J Mol Sci . 2024 Aug; 25(16). PMID: 39201357
Erastin (ER) induces cell death through the formation of reactive oxygen species (ROS), resulting in ferroptosis. Ferroptosis is characterized by an accumulation of ROS within the cell, leading to an...
3.
Silver B, Brooks A, Gerrish K, Tokar E
Int J Mol Sci . 2024 May; 25(10). PMID: 38791569
Early detection of neurological conditions is critical for timely diagnosis and treatment. Identifying cellular-level changes is essential for implementing therapeutic interventions prior to symptomatic disease onset. However, monitoring brain tissue...
4.
Silver B, Kreutz A, Weick M, Gerrish K, Tokar E
Front Oncol . 2024 May; 14:1393930. PMID: 38706609
Detrimental side effects of drugs like doxorubicin, which can cause cardiotoxicity, pose barriers for preventing cancer progression, or treating cancer early through molecular interception. Extracellular vesicles (EVs) are valued for...
5.
Silver B, Zhang S, Rabie E, Nelson C
J Cell Sci . 2021 Jul; 134(13). PMID: 34313313
Membrane voltage (Vm) plays a critical role in the regulation of several cellular behaviors, including proliferation, apoptosis and phenotypic plasticity. Many of these behaviors are affected by the stiffness of...
6.
Silver B, Wolf A, Lee J, Pang M, Nelson C
Mol Biol Cell . 2020 Jun; 31(16):1691-1702. PMID: 32520653
Patterns of proliferation are templated by both gradients of mechanical stress as well as by gradients in membrane voltage (Vm), which is defined as the electric potential difference between the...
7.
Silver B, Nelson C
Front Cell Dev Biol . 2018 Mar; 6:21. PMID: 29560350
Cancer is a complex, heterogeneous group of diseases that can develop through many routes. Broad treatments such as chemotherapy destroy healthy cells in addition to cancerous ones, but more refined...