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Brian A John

Explore the profile of Brian A John including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Midgley I, Fitzpatrick K, Taylor L, Houchen T, Henderson S, Wright S, et al.
Drug Metab Dispos . 2007 Mar; 35(6):955-67. PMID: 17360833
DB289 (pafuramidine maleate; 2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) is a prodrug of DB75 (furamidine dihydrochloride; 2,5-bis(4-guanylphenyl)furan dihydrochloride), an aromatic dication related to pentamidine that has demonstrated good efficacy against African trypanosomiasis, Pneumocystis carinii...
2.
Omori Y, Endo T, Hara Y, Nishiyama M, Midgley I, Smart C, et al.
Arzneimittelforschung . 2004 Apr; 54(3):171-8. PMID: 15112864
The absorption, distribution and excretion of pilocarpine (CAS 92-13-7) were studied after single oral doses of 14C-pilocarpine hydrochloride (CAS 54-71-7) to the Sprague-Dawley rat, administered in aqueous solution mainly at...