Brett D Keiper
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Explore the profile of Brett D Keiper including associated specialties, affiliations and a list of published articles.
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19
Citations
372
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Recent Articles
11.
Friday A, Keiper B
Biomed Res Int
. 2015 Sep;
2015:327963.
PMID: 26357652
Ultimately, the production of new proteins in undetermined cells pushes them to new fates. Other proteins hold a stem cell in a mode of self-renewal. In germ cells, these decision-making...
12.
Lee M, Mamillapalli S, Keiper B, Cha D
BMB Rep
. 2015 Aug;
49(2):93-8.
PMID: 26303971
Germline stem cells (GSCs) are the best understood adult stem cell types in the nematode Caenorhabditis elegans, and have provided an important model system for studying stem cells and their...
13.
Busada J, Niedenberger B, Velte E, Keiper B, Geyer C
Dev Biol
. 2015 Aug;
407(1):90-102.
PMID: 26254600
Spermatogonial stem cells (SSCs) must balance self-renewal with production of transit-amplifying progenitors that differentiate in response to retinoic acid (RA) before entering meiosis. This self-renewal vs. differentiation spermatogonial fate decision...
14.
Busada J, Chappell V, Niedenberger B, Kaye E, Keiper B, Hogarth C, et al.
Dev Biol
. 2014 Dec;
397(1):140-9.
PMID: 25446031
In the testis, a subset of spermatogonia retains stem cell potential, while others differentiate to eventually become spermatozoa. This delicate balance must be maintained, as defects can result in testicular...
15.
Chappell V, Busada J, Keiper B, Geyer C
Biol Reprod
. 2013 Aug;
89(3):61.
PMID: 23926285
The basic tenets of germ cell development are conserved among metazoans. Following lineage commitment in the embryo, germ cells proliferate, transition into meiosis, and then differentiate into gametes capable of...
16.
Contreras V, Friday A, Morrison J, Hao E, Keiper B
PLoS One
. 2011 Sep;
6(9):e24444.
PMID: 21909434
Apoptosis is a natural process during animal development for the programmed removal of superfluous cells. During apoptosis general protein synthesis is reduced, but the synthesis of cell death proteins is...
17.
Song A, Labella S, Korneeva N, Keiper B, Aamodt E, Zetka M, et al.
J Cell Sci
. 2010 Jun;
123(Pt 13):2228-37.
PMID: 20530576
Caenorhabditis elegans expresses five family members of the translation initiation factor eIF4E whose individual physiological roles are only partially understood. We report a specific role for IFE-2 in a conserved...
18.
Henderson M, Cronland E, Dunkelbarger S, Contreras V, Strome S, Keiper B
J Cell Sci
. 2009 Apr;
122(Pt 10):1529-39.
PMID: 19383718
Fertility and embryonic viability are measures of efficient germ cell growth and development. During oogenesis and spermatogenesis, new proteins are required for both mitotic expansion and differentiation. Qualitative and quantitative...
19.
Dinkova T, Keiper B, Korneeva N, Aamodt E, Rhoads R
Mol Cell Biol
. 2004 Dec;
25(1):100-13.
PMID: 15601834
The mRNA cap-binding protein eukaryotic translation initiation factor 4E (eIF4E) participates in protein synthesis initiation, translational repression of specific mRNAs, and nucleocytoplasmic shuttling. Multiple isoforms of eIF4E are expressed in...
20.
Miyoshi H, Dwyer D, Keiper B, Jankowska-Anyszka M, Darzynkiewicz E, Rhoads R
EMBO J
. 2002 Aug;
21(17):4680-90.
PMID: 12198170
Primitive eukaryotes like Caenorhabditis elegans produce mRNAs capped with either m(7)GTP or m(3)(2,2,7)GTP. Caenorhabditis elegans also expresses five isoforms of the cap-binding protein eIF4E. Some isoforms (e.g. IFE-3) bind to...