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Brendon D Honick

Explore the profile of Brendon D Honick including associated specialties, affiliations and a list of published articles. Areas
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Citations 34
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Recent Articles
1.
Dilly A, Honick B, Frederick R, Elapavaluru A, Velankar S, Makala H, et al.
Transl Res . 2020 Nov; 229:100-114. PMID: 33164812
Abundant intraperitoneal (IP) accumulation of extracellular mucus in patients with appendiceal mucinous carcinoma peritonei (MCP) causes compressive organ dysfunction and prevents delivery of chemotherapeutic drugs to cancer cells. We hypothesized...
2.
Dilly A, Honick B, Lee Y, Bartlett D, Choudry H
Orphanet J Rare Dis . 2020 Aug; 15(1):211. PMID: 32811515
Background: Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticulum stress...
3.
Dilly A, Honick B, Lee Y, Bartlett D, Choudry H
Cancer Med . 2020 Jan; 9(5):1753-1767. PMID: 31958897
Molecular-targeted therapies have demonstrated disappointing results against most advanced solid cancers. This may largey be attributed to irrational drug use against unselected cancers. We investigated the efficacy of dual MEK-PI3K...
4.
Dilly A, Honick B, Lee Y, Guo Z, Zeh H, Bartlett D, et al.
Oncotarget . 2018 Jan; 8(63):106888-106900. PMID: 29290997
Cancer cells aberrantly express mucins to enhance their survival. Relative chemoresistance of appendiceal pseudomyxoma peritonei (PMP) is attributed to abundant extracellular mucin 2 (MUC2) protein production. We hypothesized that simultaneous...